Verbascoside
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- CAS-Nr.
- 61276-17-3
- Englisch Name:
- Verbascoside
- Synonyma:
- ACTEOSIDE;ISOVERBASCOSIDE;Acetoside;KUSAGININ;Kusagi;TJC 160;NSC 603831;Russetinol;Verbacoside;VERBASCOSIDE
- CBNumber:
- CB2306760
- Summenformel:
- C29H36O15
- Molgewicht:
- 624.59
- MOL-Datei:
- 61276-17-3.mol
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Verbascoside Eigenschaften
- Schmelzpunkt:
- 232℃
- Siedepunkt:
- 908.8±65.0 °C(Predicted)
- Dichte
- 1.60±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- L?slichkeit
- DMSO (Slightly), Ethyl Acetate (Very Slightly), Methanol (Slightly)
- pka
- 9.31±0.10(Predicted)
- Aggregatzustand
- Solid
- Farbe
- White to Pale Yellow
- Stabilit?t:
- Hygroscopic
- InChIKey
- FBSKJMQYURKNSU-ZLSOWSIRSA-N
- LogP
- 0.077 (est)
- CAS Datenbank
- 61276-17-3(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
S-S?tze: |
24/25 |
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WGK Germany |
2 |
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RTECS-Nr. |
LZ5786000 |
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HS Code |
29389090 |
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Toxizit?t |
LD50 oral in rat: > 5gm/kg |
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Bildanzeige (GHS) |
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Alarmwort |
Warnung |
Gefahrenhinweise |
Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
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Sicherheit |
P261 |
Einatmen von Staub vermeiden. |
P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
P302+P352 |
BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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Verbascoside Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
White solid
Verwenden
Verbascoside is an agent producing effects on anti-GBM nephritis in rats. Effective agent against glomerulonephritis. Phenolic anti-oxidant agent.
Enzyminhibitor
This plant glycoside and antioxidant (FW = 624.60 g/mol; CAS 61276-173), also known as verbascoside, inhibits TNFa-mediated apoptosis in LPSstimulated macrophages as well as 1-methyl-4-phenylpyridiniuminduced apoptosis in cerebellar granule neurons. It also inhibits proliferation of human promyelocytic HL-60 leukemia cells by inducing cell cycle arrest at the G0/G1 phase, followed by differentiation into monocytes. Acteoside inhibits PMA-induced invasion and migration of human fibrosarcoma cells by Ca2+-dependent CaMK/ERK and JNK/NFκB-signaling pathways. Acteoside thus shows the potential as antimetastatic agent. Another intriguing finding is that acteoside inhibits amyloid-β aggregation. Target(s): aldose reductase; protein kinase C; integrase, HIV-1; peptidyl-dipeptidase A, or angiotensin-converting enzyme; tyrosinase, or monophenol monooxygenase; 5-lipoxygenase, or arachidonate 5-lipoxygenase.
Verbascoside Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Verbascoside Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 309)Lieferanten
61276-17-3()Verwandte Suche:
- glucopyranoside,2-(3,4-dihydroxyphenyl)ethyl3-o-(6-deoxy-alpha-l-mannopyranos
- ACTEOSIDE :B-D-GLUCOPYRANOSIDE, 2-(3,4-DIHYDROXYPHENYL)ETHYL 3-O-(6-DEOXY-A-L-MANNOPYRANOSYL)-,4-[3-(3,4-DIHYDROXYPHENYL)-2-PROPENOATE],(E)-,
- Extract from Verbena minutiflora (B864379)
- [(2R,3R,4R,5R,6R)-6-[2-(3,4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
- VERBASCOSIDE WITH HPLC
- 2-(3,4-Dihydroxyphenyl)ethyl 3-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside 4-[(E)-3-(3,4-dihydroxyphenyl)propenoate]
- 3,4-Dihydroxyphenethyl alcohol acteoside
- Verbacoside
- Acteoside(Verbascoside)
- Distinctive PhytosteM Lilac
- Verbascoside ,98%
- NSC 603831
- Russetinol
- StereosperMin
- TJC 160
- Verbascoside(Acteoside)
- Verbascoside, froM Cistanche deserticola Y.C.Ma
- VERBASCOSIDE
- B-D-GLUCOPYRANOSIDE, 2-(3,4-DIHYDROXYPHENYL)ETHYL 3-O-(6-DEOXY-ALPHA-L-MANNOPYRANOSYL)-,4-[3-(3,4-DIHYDROXYPHENYL)-2-PROPENOATE],(E)-
- 4-(3-(3,4-dihydroxyphenyl)-2-propenoate),(e)-beta-d-yl)
- Verbascoside
[(2R,3R,4R,5R,6R)-6-[2-(3,4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
- β-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl 3-O-(6-deoxy-α-L-mannopyranosyl)-, 4-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate]
- Nano Liposomal Acteoside
- Verbascoside, 98%, from Cistanche deserticola Y.C.Ma
- Acteoside Kusaginin 61276-17-3
- Kusagi
- Acteoside Standard
- 2-(3,4-Dihydroxyphenyl)ethyl 3-O-(6-Deoxy-alpha-L-mannopyranosyl)-4-O-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]-beta-D-glucopyranoside
- Verbascoside USP/EP/BP
- Acetoside
- ISOVERBASCOSIDE
- ACTEOSIDE
- Cistanche Deserticola Extract Acteoside
- KUSAGININ
- (2R,3R,4R,5R,6R)-6-(3,4-Dihydroxyphenethoxy)-5-hydroxy-2-(hydroxymethyl)-4-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-3-yl (E)-3-(3,4-dihydroxyphenyl)acrylate
- Verbascoside (15 mg)
- 61276-17-3
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- Miscellaneous Natural Products