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Isosorbiddinitrat

Isosorbide dinitrate Struktur
87-33-2
CAS-Nr.
87-33-2
Bezeichnung:
Isosorbiddinitrat
Englisch Name:
Isosorbide dinitrate
Synonyma:
ISDN;isordil;sorbide;carvasin;sorbitrate;Lion's Mane;dilatrate-sr;Isosorbide dinitrate CRS;(3R,3aS,6S,6aS)-hexahydrofuro[3,2-b]furan-3,6-diyl dinitrate;cardis
CBNumber:
CB2226929
Summenformel:
C6H8N2O8
Molgewicht:
236.14
MOL-Datei:
87-33-2.mol

Isosorbiddinitrat Eigenschaften

Schmelzpunkt:
700C
alpha 
D20 +135° (alc)
Siedepunkt:
378.59°C (rough estimate)
Dichte
1.7503 (rough estimate)
Brechungsindex
1.5010 (estimate)
storage temp. 
-20°C Freezer
L?slichkeit
Undiluted isosorbide dinitrate is very slightly soluble in water, very soluble in acetone, sparingly soluble in ethanol (96 per cent). The solubility of the diluted product depends on the diluent and its concentration.
Aggregatzustand
Solid
Farbe
White to Off-White
Wasserl?slichkeit
549.7mg/L(25 ºC)
BCS Class
3
InChIKey
MOYKHGMNXAOIAT-JGWLITMVSA-N
LogP
1.31 at 25℃
CAS Datenbank
87-33-2(CAS DataBase Reference)
EPA chemische Informationen
D-Glucitol, 1,4:3,6-dianhydro-, dinitrate (87-33-2)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xn
R-S?tze: 5-22
S-S?tze: 36
RIDADR  UN 2907
HazardClass  4.1
PackingGroup  II
HS Code  2932999000
Giftige Stoffe Daten 87-33-2(Hazardous Substances Data)
Toxizit?t LD50 oral in rat: 747mg/kg
Bildanzeige (GHS) GHS hazard pictogramsGHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
Sicherheit
P210 Von Hitze, hei?en Oberfl?chen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen.
P230 Feucht halten mit …
P233 Beh?lter dicht verschlossen halten.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P370+P380+P375 Bei Brand: Umgebung r?umen. Wegen Explosionsgefahr Brand aus der Entfernung bek?mpfen.
P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

Isosorbiddinitrat Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R5:Beim Erw?rmen explosionsf?hig.
R22:Gesundheitssch?dlich beim Verschlucken.

S-S?tze Betriebsanweisung:

S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Chemische Eigenschaften

white to light yellow crystal powde

Verwenden

Isosorbide dinitrate is also used in chronic cardiac insufficiency for preventing angina pectoris attacks. It is a long-lasting drug.

Allgemeine Beschreibung

A crystalline solid. May be toxic by ingestion. Used to make pharmaceuticals. Used as a heart drug.

Air & Water Reaktionen

Highly flammable. Slightly soluble in water.

Reaktivit?t anzeigen

Nitroalkanes, such as Isosorbide dinitrate, range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction that culminates in a detonation. Nitroalkanes are milder oxidizing agents, but still react violently with reducing agents at higher temperature and pressures. Nitroalkanes react with inorganic bases to form explosive salts. The presence of metal oxides increases the thermal sensitivity of nitroalkanes. Nitroalkanes with more than one nitro group are generally explosive. Nitroalkanes are insoluble in water. This heart drug is detonable when dry, but non-explosive with 30% of water.

Health Hazard

Fire may produce irritating and/or toxic gases. Contact may cause burns to skin and eyes. Contact with molten substance may cause severe burns to skin and eyes. Runoff from fire control may cause pollution.

Brandgefahr

Flammable/combustible material. May be ignited by friction, heat, sparks or flames. Some may burn rapidly with flare burning effect. Powders, dusts, shavings, borings, turnings or cuttings may explode or burn with explosive violence. Substance may be transported in a molten form at a temperature that may be above its flash point. May re-ignite after fire is extinguished.

Sicherheitsprofil

Moderately toxic by ingestion, intraperitoneal, intramuscular, and subcutaneous routes. Experimental reproductive effects. Mutation data reported. A flammable solid. When heated to decomposition it emits toxic fumes of NOx. A coronary vasodilator. See also NITRATES.

Isosorbiddinitrat Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Isosorbiddinitrat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 293)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Wuhan Fortuna Chemical Co., Ltd
+86-027-59207850
info@fortunachem.com China 5975 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325
sales1@chuanghaibio.com China 5889 58
airuikechemical co., ltd.
+undefined86-15315557071
sales02@sdzhonghuimaterial.com China 983 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806
sales@capot.com China 29791 60
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21634 55
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679 +8618949832763
info@tnjchem.com China 2986 55
Xiamen AmoyChem Co., Ltd
+86-86-5926051114 +8618959220845
sales@amoychem.com China 6383 58
BOC Sciences
+1-631-485-4226
inquiry@bocsci.com United States 19553 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873
sales@chemdad.com China 39894 58
Hebei shuoxi biotechnology co. LTD
+8613081092107
CHINA 964 58

87-33-2(Isosorbiddinitrat)Verwandte Suche:


  • isosorbide dinitrates
  • Isosorbide USP2000,BP98
  • Isosorbide Dinitrate 40% EU or BP
  • ISOSORBIDE DINITRATE, EP STANDARD
  • ISOSORBIDE DINITRATE, 97+%
  • ISOSORBIDE DINITRATE(CONTAINS APPROX. 60% LACTOSE) MM(CRM STANDARD)
  • ISOSORBIDE DINITRATE, USP23 50%
  • ISOSORBIDE DINITRATE IMP. B (EP): ISOSORBIDE 2-NITRATE MM(CRM STANDARD)
  • ISOSORBIDE DINITRATE IMP. C (EP): ISOSORBIDE 5-NITRATE MM(CRM STANDARD)
  • 1,4:3,6-dianhydro-,dinitrate,d-glucito
  • 1,4:3,6-dianhydro-d-glucitodinitrate
  • 1,4:3,6-dianhydrosorbitol2,5-dinitrate
  • cardis
  • carvanil
  • [(3S,3aS,6R,6aS)-6-Nitrooxy-2,3,3a,5,6,6a-hexahydrofuro[2,3-d]furan-3-yl] nitrate
  • Isosorbitol dinitrate
  • Isosorbide dinitrate,ISDN
  • Diluted Isosorbide Dinitrate (500 mg of 25% mixture with mannitol)
  • Isosorbide Dinitrate(contains approx. 60% Lactose)
  • Isosorbide Dinitrate EP
  • cedocard
  • claodical
  • corosorbide
  • dianhydrosorbitol2,5-dinitrate
  • dinitrosorbide
  • flindix
  • frandol
  • harrical
  • iso-bid
  • isochron
  • isoket
  • isorbid
  • isordiltembids
  • korodil
  • laserdil
  • maycor
  • nitrosorbid
  • nitrosorbide
  • resoidan
  • rigedal
  • sorate-10
  • sorate-5
  • sorbangil
  • sorbide,dinitrate
  • sorbidenitrate
  • sorbidilat
  • sorbidinitrate
  • sorbidnitrate
  • sorbonit
  • sorquad
  • sorquat
  • sst-101
  • tyb3215
  • vascardin
  • vasorbate
  • 1,4:3,6-dianhydro-d-glucitol dinitrate
  • ISOSORBIDE DINITRATE
  • 1,4:3,6-Dianhydrosorbitol 2,5-Dinitrate, Carvasin
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