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INOS

INOS Struktur
CAS-Nr.
Englisch Name:
INOS
Synonyma:
INOS;NOS2;NOS2A;NOS II;macNOS;NOS III;HEP-NOS;inducible;MACROPHAGE;EC 1.14.13.39
CBNumber:
CB2106409
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

INOS Eigenschaften

storage temp. 
−70°C
Aggregatzustand
buffered aqueous solution

Sicherheit

WGK Germany  1

INOS Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Nitric Oxide Synthase, Inducible from mouse has been used in immunohistochemical studies. It is also used to evaluate the therapeutic efficacy of inducible nitric oxide synthase (NOS) on reperfusion-induced microcirculatory alterations and hemodynamic adverse effects in the microvasculature of skeletal muscle.

Allgemeine Beschreibung

Inducible nitric oxide synthase (iNOS), also known as inflammatory nitric oxide synthase, is a calcium independent isoenzyme, involved in synthesis of nitric oxide (NO). It is a soluble enzyme encoded by the gene mapped to mouse chromosome 11. iNOS is active in dimeric form and its activity is induced by cytokines and various other stimuli. iNOS is expressed in various inflammatory conditions.

Biochem/physiol Actions

Tumor-derived inducible nitric oxide synthase (iNOS) plays a vital role in stimulating tumor growth and vessel maturation. Therefore, it is considered to be a potential therapeutic target for anti-vascular cancer therapies. Unchecked activity of iNOS leads to overproduction of nitric oxide (NO), which is toxic for living cells. iNOS activity can be controlled at both transcription and translational level by regulating protein stability, dimerization, phosphorylation, cofactor binding and availability of oxygen and L-arginine as substrates. iNOS plays a vital role in excisional wound repair and exhibits gene therapy strategy to advance wound healing process in iNOS-deficient conditions such as diabetes and steroid treatment.

INOS Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


INOS Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 34)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51456 80
Guangzhou Tomums Life Science Co., Ltd. 020-31155029 18902330969
sales@tomums.cn China 4696 58
Shanghai Universal Biotech Co.,Ltd 13774214275
zhouzz@univ-bio.com China 24994 58
ChemeGen 中國 18818260767
2625930290@qq.com China 6973 58
Shanghai Yaji Biological Technology Co., Ltd. 021-34661275 15301693058
yajikit@163.com China 9670 58
Shanghai Huzhen Industrial Co., LTD 021-60345367 13916550749
sales@shzbio.com China 9966 58
Biolab Reagents 027-65279366 18108604862
products@biolabreagent.com China 9818 58

()Verwandte Suche:


  • EC 1.14.13.39
  • INDUCIBLE NITRIC OXIDE SYNTHASE (MURINE RECOMBINANT)
  • INDUCIBLE NITRIC OXIDE SYNTHASE (MURINE MACROPHAGE)
  • INDUCIBLE NITRIC OXIDE SYNTHASE
  • INDUCIBLE NITRIC OXIDE SYNTHASE MOUSE
  • INOS
  • INOS, MOUSE MACROPHAGE
  • INOS, MOUSE, RECOMBINANT
  • INOS (MURINE MACROPHAGE)
  • INOS (MURINE RECOMBINANT)
  • NITRIC OXIDE SYNTHASE, INDUCIBLE
  • NITRIC OXIDE SYNTHASE, INDUCIBLE MOUSE
  • NITRIC OXIDE SYNTHASE, INDUCIBLE, MOUSE MACROPHAGE
  • NITRIC OXIDE SYNTHASE, INDUCIBLE, MOUSE, RECOMBINANT
  • NITRIC OXIDE SYNTHASE, INDUCIBLE, MOUSE, RECOMBINANT, E COLI
  • NOS II
  • NOS III
  • NOS II, INDUCIBLE MOUSE
  • NOS II (MURINE MACROPHAGE)
  • NOS II (MURINE RECOMBINANT)
  • NOS (INDUCIBLE)
  • Inducible Nitric Oxide Synthase, iNOS, macNOS, NOS II
  • Nitric Oxide Synthase, Inducible from mouse
  • Anti-INOS, N-Terminal antibody produced in rabbit
  • HEP-NOS
  • inducible
  • inducible NOS
  • Anti-INOS, C-Terminal antibody produced in rabbit
  • MACROPHAGE
  • ANTI-NOS2A (CENTER) antibody produced in rabbit
  • Hepatocyte NOS
  • Inducible NO synthase
  • Nitric Oxide Synthase, Inducible human
  • NOS2
  • NOS2A
  • macNOS
  • ANTI-NOS2A(N-TERMINAL) antibody produced in rabbit
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