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4-Acetyl-1-(β-D-ribofuranosyl)cytosin

N4-Acetylcytidine Struktur
3768-18-1
CAS-Nr.
3768-18-1
Bezeichnung:
4-Acetyl-1-(β-D-ribofuranosyl)cytosin
Englisch Name:
N4-Acetylcytidine
Synonyma:
N-Acetylcytidine;Ac-rC;Acetylcytidine;rC(Ac);N4-Ac-Cr;N4-Ac-rC;ACETYL CYTOSINE;n-acetyl-cytidin;4-Acetylcytidine;N4-ACETYLCYTIDINE
CBNumber:
CB1207392
Summenformel:
C11H15N3O6
Molgewicht:
285.25
MOL-Datei:
3768-18-1.mol

4-Acetyl-1-(β-D-ribofuranosyl)cytosin Eigenschaften

Schmelzpunkt:
199 °C (dec.)(lit.)
Dichte
1.72±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
L?slichkeit
DMSO (Slightly, Heated), Methanol (Slightly, Heated)
pka
10.21±0.20(Predicted)
Aggregatzustand
Solid
Farbe
White to Pale Yellow
PH
<1.5
maximale Wellenl?nge (λmax)
247,297 (pH 7)
CAS Datenbank
3768-18-1(CAS DataBase Reference)
NIST chemische Informationen
Cytidine, n-acetyl-(3768-18-1)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xn
R-S?tze: 20/21/22-36/37/38
S-S?tze: 36-36/37/39-26
WGK Germany  3
HS Code  29335990
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

4-Acetyl-1-(β-D-ribofuranosyl)cytosin Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.

S-S?tze Betriebsanweisung:

S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Beschreibung

N4-Acetylcytidine is a modified nucleoside and endogenous urinary nucleoside product of the degradation of tRNA. N4-Acetylcytidine is a biological marker for various cancers with elevated concentrations present in urine. tRNA has been shown to be excreted in abnormal amounts in the urine of cancer patients. tRNA from neoplastic tissue had a much more rapid turnover rate than the tRNA from the corresponding normal tissue. Evidence indicates that methylation of tRNA occurs only after synthesis of the intact macromolecule. Because there are no specific enzyme systems to incorporate the modified nucleosides into the macromolecular nucleic acid, these nucleosides once released in the process of tRNA turnover cannot be reutilized, nor are they further degraded, but are excreted in urine.
N4-Acetylcytidine is also a partially protected cytidine and therefore can be used as a synthetic building block to prepare further derivatized nucleosides such as 2’,3’-dideoxycytidine.

Verwenden

N4-Acetylcytidine (cas# 3768-18-1) is a nucleotide-derived metabolite used as biomarkers for diagnosis of inflammation-related diseases.

Definition

ChEBI: N(4)-acetylcytidine is cytidine in which one of the exocyclic amino hydrogens is substituted by an acetyl group. It has a role as a metabolite. It is a member of cytidines, a member of acetamides and a secondary carboxamide.

4-Acetyl-1-(β-D-ribofuranosyl)cytosin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


4-Acetyl-1-(β-D-ribofuranosyl)cytosin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 212)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Zhejiang Hengkang Pharmaceutical Co., Ltd.
+86-576-83372028 +86-18868723926
bd1@hengkangpharm.cn China 119 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886
info@dakenam.com China 18751 58
Shanghai Bojing Chemical Co.,Ltd.
+86-86-02137122233 +8613795318958
bj1@bj-chem.com China 299 55
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29880 58
Jinan Carbotang Biotech Co.,Ltd.
+8615866703830
figo.gao@foxmail.com China 8497 58
Accela ChemBio Inc.
+1-858-6993322
info@accelachem.com United States 17777 58
Xiamen AmoyChem Co., Ltd
+86-86-5926051114 +8618959220845
sales@amoychem.com China 6383 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873
sales@chemdad.com China 39894 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49374 58
Antai Fine Chemical Technology Co.,Limited
18503026267
info@antaichem.com CHINA 9636 58

3768-18-1(4-Acetyl-1-(β-D-ribofuranosyl)cytosin)Verwandte Suche:


  • 4-Acetyl-1-(beta-D-ribofuranosyl)cytosine
  • ACETYL CYTOSINE
  • N4-ACETYLCYTIDINE
  • 4-Acetylcytidine
  • Acetamide, N-(1,2-dihydro-2-oxo-1-beta-D-ribofuranosyl-4-pyrimidinyl)-
  • n-acetyl-cytidin
  • N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxo-pyrimidin-4-yl]ethanamide
  • N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl]-2-keto-pyrimidin-4-yl]acetamide
  • N4-Acetyl-D-cytidine
  • N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide
  • N4 CACETYLCYTIDINE
  • N(sup 4)-acetylcytidine
  • N4-Acetylcytidine
  • N4-Ac-Cr
  • N4-Ac-rC
  • N4-Acetylcytidine, 97.5%
  • N4-Acetylcytidine, 97.5%
  • Cytidine, N-acetyl-
  • N4-Acetylcytidine USP/EP/BP
  • Acetylcytidine
  • N-Acetylcytidine
  • Ac-rC
  • N4-Acetyl cytidine,RNA modified nucleoside ac4C
  • RNA modified nucleoside ac4C
  • rC(Ac)
  • Cytidine Impurity 1 (N4-Acetylcytidine)
  • 3768-18-1
  • C11H15N3O6
  • Nucleoside Analogs
  • Nucleosides, Nucleotides, Oligonucleotides
  • Biochemicals and Reagents
  • BioChemical
  • Biochemicals and Reagents
  • Nucleoside Analogs
  • Nucleosides, Nucleotides, Oligonucleotides
  • Nucleic acids
  • Modified(deoxy)nucleoside
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