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Ipriflavone

Ipriflavone Struktur
35212-22-7
CAS-Nr.
35212-22-7
Englisch Name:
Ipriflavone
Synonyma:
Ipriavone;Ipriflavon;7-ISOPROPOXYISOFLAVONE;Ipriflavone (Osteofix);tc80;osten;fl113;osteofix;YAMBOLAP;Iprosten
CBNumber:
CB0698496
Summenformel:
C18H16O3
Molgewicht:
280.32
MOL-Datei:
35212-22-7.mol

Ipriflavone Eigenschaften

Schmelzpunkt:
116-120 °C(lit.)
Siedepunkt:
363.04°C (rough estimate)
Dichte
1.2170 (rough estimate)
Brechungsindex
1.4700 (estimate)
storage temp. 
Sealed in dry,Room Temperature
L?slichkeit
DMF:20.0(Max Conc. mg/mL);71.35(Max Conc. mM)
DMF:PBS (pH 7.2) (1:4):0.2(Max Conc. mg/mL);0.71(Max Conc. mM)
DMSO:33.11(Max Conc. mg/mL);118.11(Max Conc. mM)
Ethanol:1.5(Max Conc. mg/mL);5.35(Max Conc. mM)
Aggregatzustand
powder to crystal
Farbe
White to Almost white
Merck 
14,5074
InChI
InChI=1S/C18H16O3/c1-12(2)21-14-8-9-15-17(10-14)20-11-16(18(15)19)13-6-4-3-5-7-13/h3-12H,1-2H3
InChIKey
SFBODOKJTYAUCM-UHFFFAOYSA-N
SMILES
C1OC2=CC(OC(C)C)=CC=C2C(=O)C=1C1=CC=CC=C1
LogP
4.245 (est)
CAS Datenbank
35212-22-7(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi
R-S?tze: 36/37/38
S-S?tze: 24/25-36/37/39-27-26
WGK Germany  2
RTECS-Nr. DJ3100500
HS Code  29329990
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

Ipriflavone Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S24/25:Berührung mit den Augen und der Haut vermeiden.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S27:Beschmutzte, getr?nkte Kleidung sofort ausziehen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.

Beschreibung

Ipriflavone, a derivative of isoflavone, is a calcium metabolism regulator useful in the treatment of primary and secondary osteoporosis, as well as disorders of osteogenesis. It appears to be without significant side-effects.

Chemische Eigenschaften

white powder

Verwenden

7-Isopropoxy-3-phenyl-4H-1-benzopyran-4-one (Ipriflavone) has been used as a model drug in a study to functionalize the mesoporous bioactive glasses (MBG). Study suggested that since ipriflavone is a hydrophobic anti-osteoporotic drug, it easily attaches to the surface of MBG and results in long-term drug delivery.

Definition

ChEBI: Ipriflavone is a member of the class of isoflavones that is isoflavone in which the hydrogen at position 7 is replaced by an isopropoxy group. A synthetic isoflavone, it was formerly used for the treatment of osteoporosis, although a randomised controlled study failed to show any benefit. It is still used to prevent osteoporosis in post-menopausal women. It has a role as a bone density conservation agent. It is a member of isoflavones and an aromatic ether.

benefits

Ipriflavone is used clinically to treat osteoporosis. Bodybuilders also use ipriflavone, but enough experimental data supports this purpose. It has been shown to have anti-inflammatory and antioxidant activity. It helps to reduce bone loss, increase bone density, and reduce the risk of developing osteoporosis. It has also been found to help reduce neuroinflammation . In addition, it has been found to help reduce the risk of certain types of cancer, improve cognitive function and reduce the risk of depression.

Allgemeine Beschreibung

7-Isopropoxy-3-phenyl-4H-1-benzopyran-4-one (Ipriflavone), a synthetic flavonoid, is reported to stimulate the activity of osteoblasts. It is reported to promote the deposition of calcium and the formation of mineralized nodules by newborn rat calvarial osteoblast-like (ROB) cells as well as the activity of alkaline phosphatase. Ipriflavone, an isoflavone derivative, is a new drug used to decrease bone loss in osteoporosis.

Nebenwirkungen

Ipriflavone should be taken under medical supervision only. It can produce side effects such as stomach pain, diarrhoea, dizziness, etc. It may have a sudden increase in the WBC count if administered for six months or more. When the treatment with Ipriflavone is on, it is suggested that the WBC count should be monitored. 

Ipriflavone Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Ipriflavone Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 389)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TAIZHOU YUXIN BIOTECHNOLOGY CO,.LTD
+86-576-88902229;+86-0576-88902229 +8613968687450
yuxin@yuxchem.com China 167 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325
sales1@chuanghaibio.com China 5889 58
Sinoway Industrial co., ltd.
0592-5800732; +8613806035118
xie@china-sinoway.com China 988 58
Hebei Jingbo New Material Technology Co., Ltd
+8619931165850
hbjbtech@163.com China 1000 58
Hebei Saisier Technology Co., LTD
+86-18400010335 +86-18034520335
admin@hbsaisier.cn China 1015 58
Hebei Longbang Technology Co., LTD
+86-18633929156 +86-18633929156
admin@hblongbang.com China 941 58
HebeiShuoshengImportandExportco.,Ltd
+86-18532138899 +86-18532138899
L18532138899@163.com China 939 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806
sales@capot.com China 29791 60
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21634 55
Hangzhou FandaChem Co.,Ltd.
+8615858145714
FandaChem@Gmail.com China 9087 55

35212-22-7()Verwandte Suche:


  • osten
  • tc80
  • osteofix
  • Iprflavone
  • IPRIFLAVONE(P)
  • 7-ISOPROPOXY-3-PHENYL-4H-1-BENZOPYRAN-4-ONE 97%
  • 7-ISOPROPOXYISOFLAVONE JP
  • IOPAMIDOLUSP2960166-93-0
  • IPRIFLAVONE (7-ISOPROPOXYISOFLAVONE)
  • IPRIFLAVONE
  • 7-ISOPROPYLOXYISOFLAVONE
  • 7-Isoproxyisoflavone
  • 7-ISOPROPOXY-3-PHENYL-4H-1-BENZOPYRAN-4-ONE
  • 7-(1-methylethoxy)-3-phenyl-4h-1-benzopyron-4-one
  • YAMBOLAP
  • 7-(1-methylethoxy)-3-phenyl-4h-1-benzopyran-4-on
  • 7-(1-methylethoxy)-3-phenyl-4h-1-benzopyran-4-one
  • fl113
  • 4H-1-Benzopyran-4-one, 7-(1-methylethoxy)-3-phenyl-
  • 7-Isopropyloxy-3-phenyl-4H-1-benzopyran-4-one
  • Ipriflavone,99%
  • 7-isopropoxy-3-phenyl-4H-chromen-4-one
  • 7-Isopropoxy-3-phenyl-4H-1-benzopyran-4-one, >=99%
  • Ipriflavone (7-Isopropoxy-3-phenyl-4H-1-benzopyran-4-one)
  • Ipriflavone SynonyMs 7-Isoproxyisoflavone
  • Iprosten
  • Ipriflavone>
  • Ipriflavone RS
  • Ipriflavone USP/EP/BP
  • IpriflavoneQ: What is Ipriflavone Q: What is the CAS Number of Ipriflavone Q: What is the storage condition of Ipriflavone Q: What are the applications of Ipriflavone
  • Ipriflavon
  • 7-ISOPROPOXYISOFLAVONE
  • Ipriflavone (Osteofix)
  • Ipriavone
  • 7- Isopropyl Isoflavone
  • 3-phenyl-7-(propan-2-yloxy)-4H-chromen-4-one
  • Ipriflavone 99%min
  • Ipriflavone, ≥ 98.0%
  • Yipu Flavonoids
  • 35212-22-7
  • C18H16O3
  • Building Blocks
  • Heterocyclic Building Blocks
  • Pyrans
  • APIs
  • FINE Chemical & INTERMEDIATES
  • Iso-Flavones
  • Biochemistry
  • Flavonoids
  • Nutraceuticals
  • Food & Flavor Additives
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