2'-Hydroxyacetanilid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/38:Reizt die Augen und die Haut.
R22:Gesundheitssch?dlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
white or light brown powder.soluble in hot water and ethanol, slightly soluble in cold water.
Verwenden
An Acetaminophen (A161220) impurity.
2-Acetamidophenol is used as raw material to manufacture industrial organic chemicals.
Acetaminophen is an analgesic and antipyretic agent and used as a pain reliever to treat headache, muscle aches, and arthritis.
synthetische
Mix 2-Aminophenol , acetic acid and Acetic anhydride (i.e., crystals appear), and then directly heated on the fire until all dissolved, stop heating, cooling, water dilution, precipitation of crystals filtered dry, to 70-80 ℃ of ethanol recrystallization to obtain 2-acetamidophenol.
Definition
ChEBI: 2-acetamidophenol is a member of the class of phenols that is 2-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group. A positional isomer of paracetamol which possesses anti-inflammatory, anti-arthritic and anti-platelet aggregation properties. It has a role as a platelet aggregation inhibitor, an anti-inflammatory agent, a xenobiotic metabolite, an apoptosis inducer, an antineoplastic agent and an antirheumatic drug. It is a member of phenols and a member of acetamides.
Allgemeine Beschreibung
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
l?uterung methode
Recrystallise it from water, EtOH or Est aqueous EtOH. [Beilstein 13 H 370, 13 I 113, 13 II 171, 13 III 778.]
2'-Hydroxyacetanilid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte