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Ciprofloxacin HCl

Ciprofloxacin HCl Struktur
93107-08-5
CAS-Nr.
93107-08-5
Englisch Name:
Ciprofloxacin HCl
Synonyma:
CIPROFLOXACIN HYDROCHLORIDE;1-Cyclopropyl-6-fluoro;1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride;3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, hydrochloride;Cyproxan;BAY-o-9867;CIPROFLOXACIN HCL;Bay-09867 (hydrochloride);Clprofloxacin hydrochloride;Ciprofloxacin-HCl in Methanol
CBNumber:
CB02130396
Summenformel:
C17H18FN3O3.HCl
Molgewicht:
367.8
MOL-Datei:
93107-08-5.mol

Ciprofloxacin HCl Eigenschaften

Schmelzpunkt:
>300 ºC
storage temp. 
Sealed in dry,Room Temperature
L?slichkeit
insoluble in EtOH; ≥33.87 mg/mL in H2O; ≥9.34 mg/mL in DMSO with ultrasonic
Aggregatzustand
crystalline solid
Farbe
White to off-white
BCS Class
3
InChI
InChI=1S/C17H18FN3O3.ClH/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24;/h7-10,19H,1-6H2,(H,23,24);1H
InChIKey
DIOIOSKKIYDRIQ-UHFFFAOYSA-N
SMILES
O=C(O)C1C(=O)C2=CC(=C(C=C2N(C2CC2)C=1)N1CCNCC1)F.[H]Cl
CAS Datenbank
93107-08-5
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
S-S?tze: 24/25
HS Code  29339900
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

Ciprofloxacin HCl Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Anti-bacterial

Trademarks

Ciloxan (Alcon); Cipro (Bayer); Proquin (Esprit).

Synthese

The preparation method of ciprofloxacin HCl, its step is as follows:
a) cyclopropyl carboxylic acid is added in the organic solvent, and the adding piperazine, reacted 3～8 hours down as acid binding agent with alkali at 60～120 ℃, the monitoring cyclopropyl carboxylic acid is residual less than 2% o'clock termination reaction, stirring is cooled to 0～30 ℃, leaves standstill suction filtration;
b) add water and hydrochloric acid in the products therefrom toward a) step, under agitation be warming up to molten clearly, add activated carbon decolorizing, filtered while hot, and transfer filtrate pH to 2～4 with hydrochloric acid, and the cooling crystallization filters, rinsing, and drying makes ciprofloxacin HCl.

Ciprofloxacin HCl Upstream-Materialien And Downstream Produkte

Upstream-Materialien

2,4-Dichloro-5-fluoroacetophenone

Downstream Produkte

Decarboxy Ciprofloxacin Ciprofloxacin

Ciprofloxacin HCl Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 273)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
XINGTAI XINGJIU NEW MATERIAL TECHNOLOGY CO., LTD
+8617731987558
 xingjiu@xingjiubiotech.com China 989 58
Hebei ZB Gamay Biological Technology Co.,Ltd
+8617330018573
 info@zbvet.net China 247 58
Guangzhou Tosun Pharmaceutical Limited
+8618922120635
 sales@toref-standards.com China 998 58
Hebei Weibang Biotechnology Co., Ltd 		+8615531157085
 abby@weibangbio.com China 8810 58
Hebei Yanxi Chemical Co., Ltd. 		+8617531190177
 peter@yan-xi.com China 5857 58
XI'AN TIANGUANGYUAN BIOTECH CO., LTD. 		+86-029-86333380 18829239519
 sales06@tgybio.com China 901 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-13131129325
 sales1@chuanghaibio.com China 5889 58
shandong perfect biotechnology co.ltd 		+86-53169958659 +86-13153181156
 sales@sdperfect.com China 294 58
Henan Suikang Pharmaceutical Co.,Ltd. 		+86-18239973690 +86-18239973690
 sales@suikangpharm.com China 311 58
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD. 		+86-18600796368 +86-18600796368
 sales@sjar-tech.com China 456 58

93107-08-5()Verwandte Suche:

  • 3-Quinolinecarboxylicacid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-,hydrochloride (1:1)
  • BAY-o-9867
  • Cyproxan
  • 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid monohydrochloride
  • 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, monohydrochloride
  • Clprofloxacin hydrochloride
  • 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochloride
  • CIPROFLOXACIN HCL
  • Ciprofloxacin hydrochloride CAS 93107-08-5
  • Bay-09867 (hydrochloride)
  • Enrofloxacin EP Impurity BQ: What is Enrofloxacin EP Impurity B Q: What is the CAS Number of Enrofloxacin EP Impurity B
  • 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, hydrochloride
  • 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
  • CIPROFLOXACIN HYDROCHLORIDE
  • 1-Cyclopropyl-6-fluoro
  • Bay-09867 (hydrochloride)|||Ciprofloxacin HCl|||Ciprofloxacin hydrochloride
  • Ciprofloxacin-HCl in Methanol
  • C11668500 Ciprofloxacin hydrochloride
  • 93107-08-5
  • C17H19ClFN3O3xHCl
  • Pharmaceutical intermediate
  • 93107-08-5
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