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853-23-6

中文名稱 醋酸去氫表雄酮
英文名稱 Dehydroepiandrosterone acetate
CAS 853-23-6
分子式 C21H30O3
分子量 330.46
MOL 文件 853-23-6.mol
更新日期 2024/12/16 11:00:05
853-23-6 結(jié)構(gòu)式 853-23-6 結(jié)構(gòu)式

基本信息

中文別名
重排
醋酸脫氫異雄酮
醋酸去氫表雄酮
醋酸去氫素雄酮
乙酸脫氫異雄甾酮
去氫表雄酮醋酸酯
3-醋酸去氫表雄酮
3-乙酸脫氫異雄甾酮
乙酸反式脫氫異雄素酮
醋酸去氫表雄酮(甾體)
英文別名
skf2847
PRASTERONE ACETATE
androstenoloneacetate
3B-ACETOXY-5-ANDROSTEN-17-ONE
dehydroandrosterone 3-acetate
3β-Acetoxyandrost-5-en-17-one
DEHYDROISOANDROSTERONE ACETATE
DEHYDROISOANDROSTERONE ACATATE
3-β-acetoxy-5-androsten-17-one
Dehydroepiandrosterone acetate
所屬類別
分析化學(xué):分析標準品

物理化學(xué)性質(zhì)

熔點168-170 °C(lit.)
沸點407.89°C (rough estimate)
密度1.0998 (rough estimate)
蒸氣壓0Pa at 20℃
折射率1.5192 (estimate)
儲存條件Refrigerator
溶解度可溶于氯仿、DMSO(微溶)、甲醇(微溶)
形態(tài)固體
顏色白色至灰白色
旋光性 (optical activity)[α]20/D +2.4°, c = 2 in ethanol
水溶解性11.5mg/L(temperature not stated)
InChIInChI=1/C21H30O3/c1-13(22)24-15-8-10-20(2)14(12-15)4-5-16-17-6-7-19(23)21(17,3)11-9-18(16)20/h4,15-18H,5-12H2,1-3H3/t15-,16-,17-,18-,20-,21-/s3
InChIKeyNCMZQTLCXHGLOK-KJBVPOJVSA-N
SMILESC[C@]12CC[C@H](OC(=O)C)CC1=CC[C@@]1([H])[C@]3([H])CCC(=O)[C@@]3(C)CC[C@]21[H] |&1:1,4,13,15,21,25,r|
LogP5.1 at 20℃
CAS 數(shù)據(jù)庫853-23-6

安全數(shù)據(jù)

危險性符號(GHS)GHS hazard pictograms
GHS08
警示詞危險
危險性描述H360
安全說明22-24/25
WGK Germany3
RTECS號BV8396810

應(yīng)用領(lǐng)域

用途1
用于合成甾體激素藥物
用途2
醋酸去氫表雄酮是合成各種激素、計劃生育用品等甾體激素類藥物的重要中間體,由它可合成睪丸素、甲基睪丸素、雌二醇、雌三醇

上下游產(chǎn)品信息

醋酸去氫表雄酮價格(試劑級)
報價日期產(chǎn)品編號產(chǎn)品名稱CAS號包裝價格
2024/11/11XW08532363醋酸去氫表雄酮
dehydroisoandrosterone 3-acetate;3β-acetoxy-5-androsten-17-one;3β-hydroxyandrost-5-en-17-one acetate;dehydroepiandrosterone 3-acetate;presterone acetate
853-23-6100G659元
2024/11/11XW08532362醋酸去氫表雄酮
dehydroisoandrosterone 3-acetate;3β-acetoxy-5-androsten-17-one;3β-hydroxyandrost-5-en-17-one acetate;dehydroepiandrosterone 3-acetate;presterone acetate
853-23-625G194元
2024/11/11XW08532361醋酸去氫表雄酮
dehydroisoandrosterone 3-acetate;3β-acetoxy-5-androsten-17-one;3β-hydroxyandrost-5-en-17-one acetate;dehydroepiandrosterone 3-acetate;presterone acetate
853-23-65G54元

常見問題列表

生物活性
Dehydroepiandrosterone 3-acetate 是雄性激素/雌性激素的前體物質(zhì),能夠調(diào)節(jié)脊椎動物的攻擊性行為。
體內(nèi)研究

Dehydroisoandrosterone implants increases aggression in a laboratory-based simulated territorial intrusion. Brains of Dehydroisoandrosterone-implanted birds show higher aromatase mRNA expression in the preoptic area (POA) and higher androgen receptor mRNA expression in the periventricular nucleus of the medial striatum (pvMSt) and ventromedial nucleus of the hypothalamus (VMH). The Dehydroisoandrosterone-induced increases in aromatase expression in the POA and androgen receptor expression in the pvMSt are consistent with previously reported seasonal increases in these markers associated with naturally elevated Dehydroisoandrosterone levels. Dehydroisoandrosterone supplementation (10.2 mg/kg) alone significantly increases mice body weight (BW), muscle weight, testosterone level, and glycogen contents (liver and muscle) when compared with SC group.

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