基本信息
中文別名
尼培替丁尼匹魯替定
英文別名
NiperoditinePiperotidine
Niperotidine
PiperotidineHCl
Piperonylranitidine
Piperonylranitidinehydrochloride
N-(1,3-benzodioxol-5-ylmethyl)-N'-[2-[[5-[(dimethylamino)methyl]furfuryl]thio]ethyl]-2-nitrovinylidenediamine
N-(1,3-Benzodioxol-5-ylmethyl)-N'-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-nitro-1,1-ethenediamine
1,1-Ethenediamine, N-(1,3-benzodioxol-5-ylmethyl)-N'-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-nitro-
物理化學性質(zhì)
沸點580.1±50.0 °C(Predicted)
密度1.288±0.06 g/cm3(Predicted)
酸度系數(shù)(pKa)8.35±0.28(Predicted)
常見問題列表
生物活性
Niperotidine 是一種組胺 H2 受體 (histamine H2-receptor) 拮抗劑。靶點
histamine H2 receptor
體內(nèi)研究
Niperotidine (piperonyl-ranitidine) is a H2 blocking agent. Niperotidine is a H2-receptor antagonist structurally related to ranitidine. After oral administration, it reaches a plasmatic peak within 60-120 min and is eliminates either in the urine or in the faeces, with an enterohepatic circulation.