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764659-72-5

中文名稱 (2R,5S)-5-(4-氨基-5-氟-2-氧代-1(2H)-嘧啶基)-1,3-噻烷-2-羧酸 (1R,2S,5R)-5-甲基-2-(1-甲基乙基)環(huán)己酯
英文名稱 (2R,5S)-5-(4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-Oxathiolane-2-carboxylic acid, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester
CAS 764659-72-5
分子式 C18H26FN3O4S
分子量 399.48
MOL 文件 764659-72-5.mol
更新日期 2024/12/13 09:48:58
764659-72-5 結(jié)構(gòu)式 764659-72-5 結(jié)構(gòu)式

基本信息

中文別名
恩曲他濱薄荷酯雜質(zhì)
恩曲他濱中間體FCME
FCME(鹽酸恩曲他濱中間體)
(2R,5S)-5-(4-氨基-5-氟-2-氧代-1(2H)-嘧啶基)-1,3-噁噻烷-2-羧酸
(2R,5S)-5-(4-氨基-5-氟-2-氧代-1(2H)-嘧啶基)-1,3-噻烷-2-羧酸 (1R,2S,5R)-5-甲基-2-(1-甲基乙基)環(huán)己酯
(2R,5S)-5-(4-氨基-5-氟-2-氧代-1(2H)-嘧啶基)-1,3-噁噻烷-2-羧酸, (1R,2S,5R)-5-甲基-2-(1-甲基乙基)環(huán)己酯
(2R,5S)-(1R,2S,5R)-5-(4-氨基-5-氟-2-氧代-1(2H)-嘧啶基)-1,3-噻烷-2-羧酸(1R,2S,5R)-5-甲基-2-(1-甲基乙基)環(huán)己酯
英文別名
Emtricitabine Menthyl Ester Impurity
(2R,5S)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxa...
(2R,5S)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid
(2R,5S)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (1R,2S
(2R,5S)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic Acid (1R,2S,5R)-5-
[(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl] 5-(4-amino-5-fluoro-2-oxopyrimidin-1-yl)-1,3-oxathiolane-2-carboxylate
(2R,5S)-(1R,2S,5R)-2-Isopropyl-5-Methylcyclohexyl 5-(4-aMino-5-fluoro-2-oxopyriMidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate
(2R,5S)-5-(4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-Oxathiolane-2-carboxylic acid, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester
1,3-Oxathiolane-2-carboxylic acid, 5-(4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester, (2R,5S)-
TIANFU-CHEM (2R,5S)-5-(4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-Oxathiolane-2-carboxylic acid, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester

物理化學性質(zhì)

熔點190 - 192°C
沸點508.5±60.0 °C(Predicted)
密度1.47
儲存條件Refrigerator
溶解度氯仿(微溶)、DMSO(微溶、加熱)、甲醇(微溶、超聲處理)
酸度系數(shù)(pKa)2.40±0.10(Predicted)
形態(tài)固體
顏色灰白色至淺棕色

安全數(shù)據(jù)

危險性符號(GHS)GHS hazard pictograms
GHS07
警示詞警告
危險性描述H302-H315-H319-H335
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