66508-37-0
中文名稱
膦胺霉素
英文名稱
FOSMIDOMYCIN, SODIUM SALT
CAS
66508-37-0
分子式
C3H6NaO4P
分子量
160.04
MOL 文件
66508-37-0.mol
66508-37-0 結(jié)構(gòu)式
基本信息
中文別名
膦胺霉素 英文別名
FR31564fosmidomycin
antibioticfr31564
FR-31564, SODIUM SALT
Fosmidomycinesodiumsalt
FOSMIDOMYCIN, SODIUM SALT
sodiuM hydrogen(3-(N-hydroxyforMaMido)propyl)phosphonate
[3-(Formylhydroxyamino)propyl]phosphonic acid sodium salt
(3-(formylhydroxyamino)propyl)-phosphonicacimonosodiumsalt
(3-(formylhydroxyamino)propyl)phosphonicacidmonosodiumsalt
物理化學(xué)性質(zhì)
熔點(diǎn)189-191°C
儲(chǔ)存條件-20°C冷凍
溶解度DMSO（輕微）、甲醇（輕微、加熱）、水（輕微）
形態(tài)固體
顏色白色至米色
穩(wěn)定性吸濕性
膦胺霉素價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2024/11/08 | HY-112853 | 膦胺霉素 Fosmidomycin sodium salt | 66508-37-0 | 5 mg | 1400元 |
| 2024/11/08 | HY-112853 | 膦胺霉素 Fosmidomycin sodium salt | 66508-37-0 | 10 mM * 1 mLin Water | 1540元 |
| 2024/11/08 | HY-112853 | 膦胺霉素 Fosmidomycin sodium salt | 66508-37-0 | 10mg | 2500元 |
常見問題列表
生物活性
Fosmidomycin sodium salt 是一種磷酸抗生素和抗瘧疾藥，對(duì)革蘭氏陰性菌和革蘭氏陽性菌均有活性。體外研究
Fosmidomycin sodium salt is a phosphonic acid antibiotic, which is active against both Gram-negative and Gram-positive bacteria.
體內(nèi)研究
Animals treated intraperitoneally with dosages of >10 mg/kg of fosmidomycin are apparently free of parasites. After treatment with 5 mg/kg of fosmidomycin, parasitemias are <1%. Animals treated orally with 50 or 100 mg/kg of fosmidomycin are apparently free of parasites, and parasitemias are <1% after treatment with 20 mg/kg of drug. Recrudescence is observed when the treatment is terminated after 4 days. Mice treated with 30 mg/kg of fosmidomycin over a period of 8 days are totally cured.