532-11-6
532-11-6 結(jié)構(gòu)式
基本信息
膽維他
茴三硫
3-對(duì)甲氧苯基三硫酮
5-(對(duì)-甲氧基苯基)-1,2-二硫環(huán)戊烯-3-硫酮
茴香腦三硫酮
5-(4-methoxyphenyl)-3h-1,2-dithiole-3-thione
ANETHOLE TRITHIONE
3-(p-anisy)trithione
3-(p-Methoxyphenyl)trithione
3-(p-Methoxyphenyl)-trithione
3H-1,2-Dithiole-3-thione, 5-(p-methoxyphenyl)-
5-(4-methoxyphenyl)-3h-2-dithiole-3-thione
5-(p-Methoxyphenyl)-1,2-dithiocyclopenten-3-thione
5-(p-Methoxyphenyl)-3H-1,2-dithiole-3-thione
5-(p-methoxyphenyl)-3h-2-dithiole-3-thione
AnetholTrithione
Felviten
Heporal
Mucinol
SKF 1717
skf1717
Sufralem
Sulfarlem
Sulfogal
物理化學(xué)性質(zhì)
安全數(shù)據(jù)
應(yīng)用領(lǐng)域
制備方法
532-11-6(安全特性,毒性,儲(chǔ)運(yùn))
常見(jiàn)問(wèn)題列表
茴三硫又稱(chēng)膽維他、茴香腦三硫酮，屬于分泌性利膽藥，能明顯增強(qiáng)肝臟谷胱甘肽水平，顯著增強(qiáng)谷氨酰半胱氨酸合成酶、谷胱甘肽還原酶和谷胱甘肽硫轉(zhuǎn)移酶活性，降低谷胱甘肽過(guò)氧化酶活性，增強(qiáng)肝細(xì)胞活力，使膽汁分泌增多。不增加肝臟負(fù)擔(dān)，可降低肝臟門(mén)脈壓力，消除肝炎病灶的肝充血等癥狀，促進(jìn)肝細(xì)胞活化，有助于肝功能的改善和恢復(fù)。能保護(hù)肝臟免受肝毒性物質(zhì)的損害。能顯著增加毒蕈堿樣乙酰膽堿受體數(shù)，促進(jìn)唾液分泌。具有胃腸道M受體和β2受體調(diào)節(jié)作用，促進(jìn)胃腸蠕動(dòng)和腸管內(nèi)氣體排出。適用于治療膽囊炎、膽管炎、膽石癥以及高膽固醇血癥; 可用于急、慢性肝炎，初期肝硬化的治療;或用于消除腹脹、便秘、口臭、惡心、悶痛等消化不適。
以上信息由Chemicalbook彤彤編輯整理。
Anethole trithione, a slow-releasing H 2 S donor, is a bile secretion-stimulating drug or cholagogue that protects the liver via an increase in glutathione levels and phase II detoxifying enzymes. Anethole trithione is a potentially efficacious chemoprevention agent for lung cancer and exerts chemopreventive effects in several target organs, such as the liver and colon, by increasing the detoxification rate of carcinogens in these target organs. Anethole trithione protects blood-brain barrier integrity following cerebral ischemia.
Chronic treatment with Anethole trithione increases the salivary secretion from the rat submaxillary gland induced by electrical stimulation of the parasympathetic nerve and by injection of pilocarpine. In parallel with the enhancement of the salivary secretion, the number of the muscarinic acetylcholine receptors is significantly increased.