4431-00-9
4431-00-9 結(jié)構(gòu)式
基本信息
金精三羧酸
AURINTRICARBOXYLIC ACID
LABOTEST-BB LT00080677
TIMTEC-BB SBB005410
1,4-cyclohexadiene-1-carboxylicacid,3-(bis(3-carboxy-4-hydroxyphenyl)methylen
5-[(3-carboxy-4-hydroxyphenyl)(3-carboxy-4-oxo-2,5-cyclohexadien-benzoicaci
aluminonfreeacid
e)-6-oxo-
5,5-(3-carboxy-4-oxocyclohexa-2,5-dienylidenemethylene)di(salicylic acid)
aurinetricarboxylic acid
AURINTRICARBOXYLIC ACID FREE ACIDPRACTIC AL GRADE
Aurintricarboxylic Acid (Ata)
AURINTRICARBONIC ACID
Aurintricarboxylic acid, tech., 85%
1-Oxo-4-[bis(3-carboxy-4-hydroxyphenyl)methylene]-2,5-cyclohexadiene-2-carboxylic acid
5,5'-[(3-Carboxy-4-oxo-2,5-cyclohexadien-1-ylidene)methylene]bis(2-hydroxybenzoic acid)
物理化學(xué)性質(zhì)
安全數(shù)據(jù)
知名試劑公司產(chǎn)品信息
Aurintricarboxylic acid(4431-00-9)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2024/11/08 | A15905 | 金精三羧酸 Aurintricarboxylic acid | 4431-00-9 | 5g | 643元 |
| 2024/11/08 | A15905 | 金精三羧酸 Aurintricarboxylic acid | 4431-00-9 | 25g | 2252元 |
| 2024/11/08 | A15905 | 金精三羧酸 Aurintricarboxylic acid | 4431-00-9 | 100g | 6004元 |
常見問題列表
|
Topoisomerase II
|
rP2X1R 8.6 nM (IC 50 ) |
rP2X3R 72.9 nM (IC 50 ) |
Apoptosis
|
miRNA 0.47 μM (IC 50 ) |
Aurintricarboxylic acid strongly inhibits rP2X1Rs and rP2X3Rs with IC
50
values of 8.6 nM and 72.9 nM, respectively, and more weakly inhibits P2X2/3Rs, P2X2Rs, P2X4Rs or P2X7Rs.
Aurintricarboxylic acid inhibition of ATP-induced currents is concentration dependent.
Aurintricarboxylic acid is a non-competitive antagonist of P2X3R.
Aurintricarboxylic acid can inhibit the severe acute respiratory syndrome-associated coronavirus (SARS-CoV) and vaccinia virus.
Aurintricarboxylic acid protects MDCK cells from infection with influenza A strains PR8, NY or N.
Aurintricarboxylic acid inhibits replication of influenza A and B viruses.
Aurintricarboxylic acid inhibits neuraminidase activities of influenza A and B viruses.
Aurintricarboxylic acid inhibits TWEAK-Fn14-mediated NF-κB activation.
Aurintricarboxylic acid (10 μM;0.5-2 hours) suppresses TWEAK-Fn14-mediated NF-κB, Akt, and Src phosphorylation in GBM cells.
Aurintricarboxylic acid blocks TWEAK-stimulated Rac1 activation and TRAF2 recruitment to Fn14 cytoplasmic domain in glioma cells.
Aurintricarboxylic acid represses TWEAK-stimulated glioma cell migration and invasion without causing cell cytotoxicity.
Aurintricarboxylic acid (Compound 8) cannot regulate loading of endogenous let-7 onto AGO2 inside cultured cells, whereas can inhibit RISC loading of exogenous siRNA.
Western Blot Analysis
| Cell Line: | T98G, A172, GBM44 glioma cells |
| Concentration: | 10 μM |
| Incubation Time: | 0.5 hour, 1 hour, 2 hours |
| Result: | Abrogated TWEAK activation of downstream signals including phosphorylation of the NF-κB family member p65, Akt, and Src in all three GBM cell lines. |