4199-10-4
中文名稱
鹽酸普奈洛爾
英文名稱
(S)-(-)-PROPRANOLOL HYDROCHLORIDE
CAS
4199-10-4
EINECS 編號
224-096-0
分子式
C16H22ClNO2
MDL 編號
MFCD00064547
分子量
295.8
MOL 文件
4199-10-4.mol
更新日期
2024/06/03 14:41:39
4199-10-4 結(jié)構(gòu)式
基本信息
中文別名
鹽酸普奈洛爾 英文別名
2S-(-)-PROPANOLOL HYDROCHLORIDE(S)-(-)-1-[(1-METHYLETHYL)AMINO]-3-(1-NAPHTHALENYLOXY)-2-PROPANOL HYDROCHLORIDE
(S)-1-ISOPROPYLAMINO-3-(1-NAPHTHYLOXY)-2-PROPANOL HYDROCHLORIDE
S-(-)-PROPANOLOL HCL
S(-)-PROPRANOLOL HCL
(S)-(-)-PROPRANOLOL HYDROCHLORIDE
(S)-PROPRANOLOL HYDROCHLORIDE
(S)-[2-hydroxy-3-(naphthyloxy)propyl]isopropylammonium chloride
2-Propanol, 1-(1-methylethyl)amino-3-(1-naphthalenyloxy)-, hydrochloride, (2S)-
2-Propanol, 1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-, hydrochloride, (2S)- (9CI)
2-Propanol, 1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-, hydrochloride, (S)-
L-(-)-Propranolol hydrochloride
l-Propranolol chlorhydrate
l-Propranolol hydrochloride
S-(-)-1-Isopropylamino-3-(1-naphthoxy)-2-propanol hydrochloride
S-PROPANOLOL
(S)-1-(isopropylamino)-3-(naphthalen-1-yloxy)propan-2-ol hydrochloride
(S)-(-)-1-(1-Methylethylamino)-3-naphthalen-1-yloxy-propan-2-ol hydrochloride
(2S)-1-(1-Naphtyloxy)-3-(isopropylamino)-2-propanol·hydrochloric acid
物理化學(xué)性質(zhì)
熔點(diǎn)193-195 °C(lit.)
熔點(diǎn)193-195 °C(lit.)
儲存條件2-8°C
儲存條件2-8°C
溶解度ethanol: 10 mg/mL
溶解度乙醇：10 mg/mL
形態(tài)powder
形態(tài)粉末
顏色White to off-white
旋光性 (optical activity)[α]25/D 25.5°, c = 1.0 in ethanol(lit.)
水溶解性溶于水至100mM
BRN3574966
InChIKeyZMRUPTIKESYGQW-UQKRIMTDSA-N
CAS 數(shù)據(jù)庫4199-10-4(CAS DataBase Reference)
安全數(shù)據(jù)
應(yīng)用領(lǐng)域
用途1
The S-enantiomer of Propranolol (P831800). β鈭扐drenergic blocker. Antihypertensive; antianginal; antiarrhythmic (class II).常見問題列表
生物活性
(S)-(-)-Propranolol hydrochloride 是一種腎上腺素能受體 (β-adrenergic receptor) 拮抗劑，針對 β1，β2，和β3的 log Kd 值分別為 -8.16，-9.08 和 -6.93。(S)-(-)-Propranolol hydrochloride 可以用于高血壓，嗜鉻細(xì)胞瘤，心肌梗塞，心律不齊，心絞痛和肥大心肌病的相關(guān)研究。靶點(diǎn)
log Kd: -8.16 (β 1 -adrenergic receptor)log Kd: -9.08 (β 2 -adrenergic receptor)log Kd: -6.93 (β 3 -adrenergic receptor)