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ChemicalBook--->CAS DataBase List--->98796-53-3

98796-53-3

98796-53-3 Structure

98796-53-3 Structure
IdentificationBack Directory
[Name]

5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
[CAS]

98796-53-3
[Synonyms]

DMT-dA(bz) AMidite
Bz-dA Phosphoramidite
-deoxyadenosine-3'
DMT-dA(bz) Pharmadite
DA-CE PHOSPHORAMIDITE
DNA A PHOSPHORAMIDITE
DMT-dA-CEPhosphoramidite
dA(N-Bz) Phosphoramidite
DMT-Bz-dA phosphoramidite
DMT-dA(bz) PhosphoraMidite
5'-DMT-Bz-dA phosphoramidite
DMT-DA(BZ) AMIDITE 5G SINGLE
DMT-dA(bz) Amidite, 5g, 6pack
DMT-dA(Bz)-CE Phosphoramidite
DMT-DA(BZ) AMIDITE 10G SINGLE
DMT-dA(bz) Amidite 20g, 6 Pack
DMT-dA(bz) Amidite 8.05g, 6 Pack
2'DEOXYADENOSINE PHOSPHORAMADITE
REF DUPL: dA(bz) Phosphoramidite
2'-DEOXYADENOSINE PHOSPHORAMIDITE
DMT-dA(bz) Amidite 2g, 89, 12 Pack
DMT-dA(bz) Amidite 1g, 89, 12 Pack
DMT-DA(BZ) AMIDITE 2G AB 12 PACK
-Dimethoxytrityl)-N6-benzoyl-2'
DMT-DA(BZ) AMIDITE 1G AB 12 PACK
DMT-dA(bz) Amidite 2g, 60ml vial, 12 Pac
DMT-DA(BZ) AMIDITE 4G 60ML VIAL 12 PAC
DMT-dA(bz) Amidite 1g, 60ml vial, 12 Pac
deoxyadenosine-ce phosphoramidite for cyclone
-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
N6-benzoyl-DMT-2'-deoxyadenosine-3'-CE Phosphoramidite
5'-O-DMT-N6-Benzyoyl-2'-Deoxy Adenosine Phosphoramidite
N-blocked-5'-O-DMT 3'-CED deoxyadenosine phosphoramidite
5'-O-DMT-N6-Benzoyl-2'-deoxyadenosine 3'-CE phosphoramidite
N6-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-CE Phosphoramidite
N6-Benzoyl-5'-O-DMT-2'-deoxyadenosine-3'-CE Phosphoramidite
N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine 5'-CE phosphoramidite
N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-CE phosphoramidite
3'-O-P-5'-O-DMT-N-BZ-2'-DEOXY-ADENOSINE [DA(BZ) PHOSPHORAMIDITE]
N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-CE phosphoraMidite
N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine-3'-cyanoethyl Phosphoramidite
N6-BENZOYL-5'-O-(DIMETHOXYTRITYL)-2'-DEOXYADENOSINE-3'-N,N-DIISOPROPYL (CYANOETHYL) PHOSPHORAMIDITE
5'-Dimethoxytrityl-N-benzoyl-2'-deoxyAdenosine,3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
5'-O-(4,4'-DIMETHOXYTRITYL)-N6-BENZOYL-2'-DEOXYADENOSINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE
N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite]
5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite USP/EP/BP
N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-adenosine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]
Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
(2R,3S,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl 2-cyanoethyl diisopropylphosphoramidite
[EINECS(EC#)]

685-521-7
[Molecular Formula]

C47H52N7O7P
[MDL Number]

MFCD00036314
[MOL File]

98796-53-3.mol
[Molecular Weight]

857.93
Questions And AnswerBack Directory
[Physical form]

Powder or granules
[Color]

White to off-white
Chemical PropertiesBack Directory
[density ]

1.23 at 20℃
[vapor pressure ]

0-0Pa at 20-50℃
[storage temp. ]

Sealed in dry,2-8°C
[solubility ]

soluble, clear
[form ]

powder or granules
[pka]

7.87±0.43(Predicted)
[color ]

white to off-white
[InChIKey]

GGDNKEQZFSTIMJ-AKWFTNRHSA-N
[SMILES]

O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C3C(=C(N=CN=3)NC(=O)C3=CC=CC=C3)N=C2)C[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N
[LogP]

7.14 at 20℃
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302+H312+H332-H315-H319-H335
[Precautionary statements ]

P261-P280-P305+P351+P338
[WGK Germany ]

3
[HS Code ]

29349990
Hazard InformationBack Directory
[General Description]

DMT-dA(bz) Phosphoramidite belongs to the group of DNA Phosphoramidites. Its key features include:
Exocyclic amine functions are protected by a benzoyl group (dA(bz) anddC(bz)) or isobutyryl group (dG(ib)).
Recommended cleavage and deprotection conditions are 8 hours at 55 °Cor 24 hours at room temperature using concentrated ammonia solution,for standard base-protected oligonucleotides.
The high coupling efficiency of Proligo′s DNA phosphoramidites leads tohigh-yield and high-quality oligonucleotides.
[Uses]

N6-Benzoyl-2’-deoxy-5’-O-DMT-cytidine 3’-CE Phosphoramidite is used to prepare antisense oligonucleotides containing conformationally constrained methoxyaminomethylene and aminooxymethylene and aminomethylene bridged nucleoside analogs.
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