| Identification | More | [Name]
5-Nitrosalicylic acid | [CAS]
96-97-9 | [Synonyms]
2-HYDROXY-5-NITROBENZOIC ACID
5-NITRO-2-HYDROXY-BENZOIC ACID
5-NITROSALICYLIC ACID
ANILOTIC ACID
AURORA KA-2534
RARECHEM AL BE 0192
TIMTEC-BB SBB006535
2-hydroxy-5-nitro-benzoicaci
5-Nitrosalicylicacid,98%
Benzoic acid, 2-hydroxy-5-nitro-
2-Hydroxy-3-nitrobenzoic acid 98%
2-HYDROXY-5-NITROBENZOIC ACID/5-NITROSALICYLIC ACID
5-NITROSALICYLIC ACID 99%
5-Nitro-o-hydroxybenzoic acid | [EINECS(EC#)]
202-548-8 | [Molecular Formula]
C7H5NO5 | [MDL Number]
MFCD00007338 | [Molecular Weight]
183.12 | [MOL File]
96-97-9.mol |
| Chemical Properties | Back Directory | [Appearance]
yellow powder | [Melting point ]
228-230 °C(lit.)
| [Boiling point ]
316.77°C (rough estimate) | [density ]
1,65 g/cm3 | [vapor pressure ]
0Pa at 25℃ | [refractive index ]
1.6280 (estimate) | [storage temp. ]
no restrictions. | [solubility ]
water: soluble1g in 1475ml(lit.) | [form ]
Liquid | [pka]
pK1:2.12 (25°C) | [color ]
Clear yellow-beige to orange-brown | [Water Solubility ]
Soluble in water 1g/1475ml . | [Merck ]
14,6632 | [BRN ]
2213719 | [InChIKey]
PPDRLQLKHRZIJC-UHFFFAOYSA-N | [LogP]
1.158 at 25℃ | [CAS DataBase Reference]
96-97-9(CAS DataBase Reference) | [EPA Substance Registry System]
96-97-9(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [TSCA ]
Yes | [HS Code ]
29182990 |
| Hazard Information | Back Directory | [Chemical Properties]
yellow powder | [Uses]
5-Nitrosalicylic Acid is a salicylic acid derivative with anti-inflammatory effect against colitis. | [Definition]
ChEBI: A monohydroxybenzoic acid in which the hydroxy group is ortho- to the carboxylic acid group and which has a nitro substituent para- to the phenolic hydroxy group. | [Synthesis Reference(s)]
Tetrahedron Letters, 36, p. 2377, 1995 DOI: 10.1016/0040-4039(95)00281-G | [General Description]
2-Hydroxy-5-nitrobenzoic acid inhibits the activity of wild type-bovine low Mr protein tyrosine phosphatase. The inhibition constant has been evaluated. | [Flammability and Explosibility]
Nonflammable | [Purification Methods]
Crystallise the acid from Me2CO (charcoal), then twice more from Me2CO alone, aqueous EtOH (m 234-236o) or H2O (m 232-233o). [Beilstein 10 III 197, 10 IV 255.] |
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