| Identification | More | [Name]
2-Bromotoluene | [CAS]
95-46-5 | [Synonyms]
1-BROMO-2-METHYLBENZENE
2-BROMO-1-METHYLBENZENE
2-BROMOTOLUENE
2-Methylbromobenzene
o-Bromomethylbenzene
O-BROMOTOLUENE
o-methylphenyl bromide
ORTHO BROMO TOLUENE
O-TOLYL BROMIDE
1-Brom-2-methylbenzol
1-bromo-2-methyl-benzen
1-Methyl-2-bromobenzene
2-bromo-toluen
2-Bromtoluol
2-Methylphenylbromide
2-Tolyl bromide
2-tolylbromide
a13-26648
Benzene,1-bromo-2-methyl-
o-bromo-toluen | [EINECS(EC#)]
202-421-7 | [Molecular Formula]
C7H7Br | [MDL Number]
MFCD00000068 | [Molecular Weight]
171.03 | [MOL File]
95-46-5.mol |
| Chemical Properties | Back Directory | [Appearance]
liquid | [Melting point ]
-27 °C (lit.) | [Boiling point ]
58-60 °C/10 mmHg (lit.) | [density ]
1.422 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.555(lit.)
| [Fp ]
174 °F
| [storage temp. ]
2-8°C | [form ]
Liquid | [color ]
Clear colorless to light yellow | [Specific Gravity]
1.422 | [Stability:]
Stable. Incompatible with strong oxidizing agents. | [Water Solubility ]
<0.1 g/100 mL at 15 ºC | [Merck ]
14,1439 | [BRN ]
1904176 | [Dielectric constant]
4.2800000000000002 | [CAS DataBase Reference]
95-46-5(CAS DataBase Reference) | [NIST Chemistry Reference]
Benzene, 1-bromo-2-methyl-(95-46-5) | [EPA Substance Registry System]
95-46-5(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S37/39:Wear suitable gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [RTECS ]
XS7965500
| [Hazard Note ]
Harmful/Irritant | [TSCA ]
Yes | [PackingGroup ]
III | [HS Code ]
29036990 | [Hazardous Substances Data]
95-46-5(Hazardous Substances Data) |
| Hazard Information | Back Directory | [General Description]
Clear colorless to pale beige liquid. | [Reactivity Profile]
O-BROMOTOLUENE(95-46-5) reacts with strong oxidizing agents. | [Air & Water Reactions]
Insoluble in water. | [Fire Hazard]
This chemical is combustible. | [Chemical Properties]
liquid | [Uses]
2-Bromotoluene was used in the synthesis of (±)-isocomene. Suzuki coupling of 2-bromotoluene with phenylboronic acid using palladium nanoparticles supported on alumina-based oxides as catalyst has been reported. 2-Bromotoluene is used in manufacturing pharmaceuticals (especially for nonsteroidal antiinflammatory drugs; Meclofenamic acid, Mefenamic acid) and other organic compounds | [Purification Methods]
Fractionally distil it through an efficient column. It can be separated from its isomers by gas chromatography on a column of “Sil-o-cel” firebrick (30-40mesh, 80 parts) coated with 5% (20 parts) of ICI E301 con rubber with N2 carrier gas at 170o/atm and 100mL/minute and using a conductivity cell detector. [Cowley et al. J Chem Soc 1801 1959, Beilstein 5 H 304, 5 I 153, 5 II 234 5 III 704, 5 IV 825.] |
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