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ChemicalBook--->CAS DataBase List--->78416-81-6

78416-81-6

78416-81-6 Structure

78416-81-6 Structure
IdentificationBack Directory
[Name]

HL 725
[CAS]

78416-81-6
[Synonyms]

HL 725
HL 725 HCL
TREQUINSIN
Trequinsin, HCl
TREQUINSIN HYDROCHLORIDE
DTCZZBVPTHVXFA-OSMRDGEFSA-N
TREQUINSIN HYDROCHLORIDE MINIMUM 98%
4,6-trimethylphenyl)imino)--2-((monohydrochloride
Trequinsin, Hydrochloride - CAS 78416-81-6 - Calbiochem
4h-pyrimido(6,1-a)isoquinolin-4-one,2,3,6,7-tetrahydro-9,10-dimethoxy-3-methyl
9,10-DIMETHOXY-2-MESITYLIMINO-3-METHYL-2,3,6,7-TETRAHYDRO-4H-PYRIMIDO-(6,1-A)-ISOQUINOLIN-4-ONE, HCL
9,10-DIMETHOXY-2-MESITYLIMINO-3-METHYL-2,3,6,7-TETRAHYDRO-4H-PYRIMIDO-[6,1A]-ISOQUINOLIN-4-ONE HYDROCHLORIDE
2,3,6,7-Tetrahydro-9,10-dimethoxy-3-methyl-2-[(2,4,6-trimethylphenyl)imino]-4H-pyrimido[6,1-a]isoquinolin-4-onehydrochloride
2,3,6,7-TETRAHYDRO-9,10-DIMETHOXY-3-METHYL-2-[(2,4,6-TRIMETHYLPHENYL)IMINO]-4H-PYRIMIDO[6,1-A]ISOQUINOLIN-4-ONE HYDROCHLORIDE
4H-Pyrimido(6,1-A)isoquinolin-4-one, 2,3,6,7-tetrahydro-9,10-dimethoxy-3-methyl-2-((2,4,6-trimethylphenyl)imino)-, monohydrochloride
[Molecular Formula]

C24H28ClN3O3
[MDL Number]

MFCD01076563
[MOL File]

78416-81-6.mol
[Molecular Weight]

441.95
Chemical PropertiesBack Directory
[Melting point ]

210-211 °C(Solv: ethanol (64-17-5); ethyl ether (60-29-7))
[storage temp. ]

Desiccate at RT
[solubility ]

DMSO: 100 mM; Ethanol: 100 mM
[form ]

Pale yellow solid
[color ]

Light yellow to yellow
Safety DataBack Directory
[WGK Germany ]

3
[RTECS ]

UW7727000
Hazard InformationBack Directory
[Uses]

PDE inhibitor
[Biological Activity]

Extremely potent inhibitor of cGMP-inhibited phosphodiesterase (PDE3; IC 50 = 250 pM). Potently inhibits arachidonic acid-induced aggregation of human platelets (IC 50 = 50 pM). Orally active antihypertensive agent; reduces systemic blood pressure in both normotensive and hypertensive animal models.
[storage]

Desiccate at RT
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