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ChemicalBook--->CAS DataBase List--->70356-03-5

70356-03-5

70356-03-5 Structure

70356-03-5 Structure
IdentificationMore
[Name]

Cefaclor monohydrate
[CAS]

70356-03-5
[Synonyms]

CEFACLOR HYDRATE
CEFACLOR MONOHYDRATE
lilly99638hydrate
monohydrate,(6r-(6-alpha,7-beta(r*)))-ino)-3-chloro-8-oxo
panoralhydrate
3-chloro-7-D-(2-phenylglycinamido)-3-cephem-4-carboxylic acid monohydrate
Ceclor
Cefactor
(6R,7R)-7-[(2-Amino-2-phenylacetyl)amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Monohydrate
Distaclor
Keflor
Raniclor
CEFACLOR,MONOHYDRATE,USP
8-(2-AMINO-2-PHENYLACETYL)AMINO-4-CHLORO-7-OXO-2-THIA-6-AZABICYCLO[4,2,0]OCT-4-ENE-5-CARBOXYLICACID
[6R-[6α,7β(R^<*>^)]]-7-[(Aminophenylacetyl)amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2.ene-2-carboxylic acidmonohydrate
Alfatil
Panacef
8-(2-Amino-2-phenylacetyl)amino-4-chloro-7-oxo-2-thia-6-azabicyclo[4.2.0]oct-4-ene-5-carboxylic acid monohydrate
(7R)-3-Chloro-7-[[(R)-aminophenylacetyl]amino]cepham-3-ene-4-carboxylic acid sodium salt
Muco-panoral
[EINECS(EC#)]

258-909-5
[Molecular Formula]

C15H16ClN3O5S
[MDL Number]

MFCD00071999
[Molecular Weight]

385.82
[MOL File]

70356-03-5.mol
Chemical PropertiesBack Directory
[Appearance]

Crystalline Solid
[Melting point ]

>180°C (dec.)
[storage temp. ]

-20?C Freezer
[solubility ]

Slightly soluble in water, practically insoluble in methanol and in methylene chloride.
[form ]

neat
[color ]

White to Light Beige
[Usage]

Second-generation cephalosporin antibiotic. Antibacterial
[Contact allergens]

Cefaclor is a semisynthetic cephalosporin antibiotic, related to cefalexin, and a frequent inducer of serum sickness-like reactions.
[CAS DataBase Reference]

70356-03-5(CAS DataBase Reference)
Hazard InformationBack Directory
[Chemical Properties]

Crystalline Solid
[Uses]

Antibacterial;Bacterial transpeptidase inhibitor
[Uses]

Second-generation cephalosporin antibiotic. Antibacterial
[Description]

Cefaclor was found by Eli Lilly & Co. in 1976 in the course of studies on the improvement of synthetic procedures for cephalexin. The intermediates with chlorine at the 3 position of the cephem nucleus have excellent antibacterial activity. Cefaclor was selected from among the various derivatives that differed at the 7 position because of its strong activity and high bioavailability following oral administration.
[Brand name]

Ceclor (Lilly); Raniclor (Ranbaxy).
[storage]

Store at -20°C
Safety DataBack Directory
[Hazard Codes ]

Xn,Xi
[Risk Statements ]

42/43-36
[Safety Statements ]

22-36/37-45
[WGK Germany ]

2
[RTECS ]

XI0363000
[HS Code ]

2941906000
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Phosphorus pentachloride-->Acetamide-->Phenylacetic acid-->Peroxyacetic acid-->N-Chlorosuccinimide-->Methyl chloroformate-->Ozone-->Penicillin G-->Cefaclor-->trans-Methyl crotonate
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