| Identification | Back Directory | [Name]
epiberberine | [CAS]
6873-09-2 | [Synonyms]
Siberian
BerbiniuM
epiberberine
Epiberberine Chloride
11,12-Dihydro-8,9-dimethoxybenzo[a]-1,3-benzodioxolo[4,5-g]quinolizinium | [Molecular Formula]
C20H18NO4+ | [MDL Number]
MFCD01547982 | [MOL File]
6873-09-2.mol | [Molecular Weight]
336.361 |
| Chemical Properties | Back Directory | [Melting point ]
260℃ | [storage temp. ]
Amber Vial, -20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
Orange to Dark Orange |
| Hazard Information | Back Directory | [Uses]
Epiberberine Chloride, is a natural bioactive alkaloid, an isomer of Berberine (B318150), an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells. | [target]
MEK | ERK | AMPK | Akt | Fatty Acid Synthase | Raf | P450 (e.g. CYP17) | LDL | HMG-CoA Reductase | AChE | BACE | ROS |
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