| Identification | More | [Name]
2-Chloro-4-methylaniline | [CAS]
615-65-6 | [Synonyms]
1-AMINO-2-CHLORO-4-METHYLBENZENE
2-CHLORO-4-METHYLANILINE
2-CHLORO-4-TOLUIDINE
2-CHLORO-P-TOLUIDINE
3-CHLORO-4-AMINOTOLUENE
4-AMINO-3-CHLOROTOLUENE
2-Chlor-4-toluidin
2-chlor-4-toluidin(czech)
2-Chloro-4-methylbenzamine
2-chloro-4-methyl-benzenamin
2-Chloro-4-Methyl-Benzenamine
2-chloro-p-toluidin
4-Methyl-2-chloroaniline
p-Toluidine, 2-chloro-
ORTHO CHLORO PARA TOLUIDINE
2-CHLORO-PARA-TOLUIDINE
2-chlor-4-toluidine
2-CHLORO-4-METHYLANILINE/4-AMINO-3-CHLOROTOLUENE
2-Chloro-p-toluidine, 4-Amino-3-chlorotoluene
2-Chloro-4-methylaniline ,98% | [EINECS(EC#)]
210-440-7 | [Molecular Formula]
C7H8ClN | [MDL Number]
MFCD00007666 | [Molecular Weight]
141.6 | [MOL File]
615-65-6.mol |
| Chemical Properties | Back Directory | [Appearance]
The chloromethylanilines are colorless or
white crystalline solids or liquids, some have a mild
fishy odor. | [Melting point ]
7 °C (lit.) | [Boiling point ]
223-225 °C (lit.) | [density ]
1.151 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.575(lit.)
| [Fp ]
211 °F
| [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
methanol: soluble | [form ]
Liquid | [pka]
3.09±0.10(Predicted) | [color ]
Clear yellow to pale brown | [Detection Methods]
GC | [BRN ]
774514 | [CAS DataBase Reference]
615-65-6(CAS DataBase Reference) | [NIST Chemistry Reference]
Benzenamine, 2-chloro-4-methyl-(615-65-6) | [EPA Substance Registry System]
615-65-6(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin .
R22:Harmful if swallowed.
R33:Danger of cumulative effects. | [Safety Statements ]
S36/37:Wear suitable protective clothing and gloves .
S37/39:Wear suitable gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [RIDADR ]
UN 3429 6.1/PG 3
| [WGK Germany ]
3
| [RTECS ]
XU5110000
| [F ]
8-9-23 | [Hazard Note ]
Harmful | [TSCA ]
Yes | [HazardClass ]
6.1 | [PackingGroup ]
III | [HS Code ]
29214200 | [Safety Profile]
Poison by ingestion. A
severe eye and skin irritant. Mutation data
reported. When heated to decomposition it
emits toxic fumes of Cland NOx. See also
other chloro toluidine entries. | [Hazardous Substances Data]
615-65-6(Hazardous Substances Data) |
| Hazard Information | Back Directory | [Potential Exposure]
Most of the isomers are used in dyestuff manufacture. The 3-chloro-para isomer is used to kill
birds. It is marketed as pelleted bait for control of bird
populations. | [First aid]
If this chemical gets into the eyes, remove any
contact lenses at once and irrigate immediately for at least
15 minutes, occasionally lifting upper and lower lids. Seek
medical attention immediately. If this chemical contacts the
skin, remove contaminated clothing and wash immediately
with soap and water. Seek medical attention immediately.
If this chemical has been inhaled, remove from exposure,
begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if
heart action has stopped. Transfer promptly to a medical
facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce
vomiting. Do not make an unconscious person vomit.
| [Shipping]
UN2239 Chlorotoluidines, solid, Hazard Class:
6.1; Labels: 6.1-Poisonous materials. UN3429
Chlorotoluidines, liquid, Hazard Class: 6.1; Labels: 6.1-
Poisonous materials | [Incompatibilities]
Incompatible with oxidizers, strong
acids; chloroformates, and acid anhydrides, isocyanates,
aldehydes forming fire and explosive hazards. | [Chemical Properties]
clear yellow to pale brown liquid | [Chemical Properties]
The chloromethylanilines are colorless or
white crystalline solids or liquids, some have a mild
fishy odor. | [Uses]
2-Chloro-4-methylaniline was used in determination of aniline derivatives in environmental water samples using on-line combination of supported liquid membrane extraction and liquid chromatography. It was also used in determination of amines in environmental water samples by gas chromatography–mass spectrometry. | [Uses]
2-Chloro-4-methylaniline is an intermediate used to prepare reverse transcriptase inhibitors of HIV-1. |
| Questions And Answer | Back Directory | [Description]
2-Chloro-4-methylaniline was used in determination of aniline derivatives in environmental water samples using on-line combination of supported liquid membrane extraction and liquid chromatography. It was also used in determination of amines in environmental water samples by gas chromatography–mass spectrometry. It is an intermediate used to prepare reverse transcriptase inhibitors of HIV-1.
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