| Identification | More | [Name]
(R)-(-)-1-Cyclohexylethylamine | [CAS]
5913-13-3 | [Synonyms]
(R)-(-)-1-CYCLOHEXYLETHYLAMINE
(R)-1-CYCLOHEXYLETHYLAMINE
R(-)-ALPHA-METHYLCYCLOHEXANEMETHYLAMINE
Cyclohexanemethanamine, alpha-methyl-, (R)-
(R)-alpha-cyclohexanemethylamine
(R)-(-)-1-CYCLOHEXYLETHYLAMINE 98%
(r)-(-)-à-methylcyclohexanemethylamine
(r)-(-)-α-methylcyclohexanemethylamine
(R)-(-)-1-CYCLOHEXYLETHYLAMINE: CHIPROS 98%, EE 94%
(R)-(-)-1-CYCLOHEXYLETHYLAMINE, CHIPROS 98%, EE 94+%
(1R)-1-Cyclohexylethanamine
(R)-1-Cyclohexylethanamine
[(1R)-1-Cyclohexylethyl]amine
[R,(-)]-α-Methylcyclohexanemethanamine | [EINECS(EC#)]
227-634-2 | [Molecular Formula]
C8H17N | [MDL Number]
MFCD00043338 | [Molecular Weight]
127.23 | [MOL File]
5913-13-3.mol |
| Chemical Properties | Back Directory | [Melting point ]
-15°C (estimate) | [alpha ]
-3.8 º (NEAT) | [Boiling point ]
177-178 °C (lit.) | [density ]
0.866 g/mL at 20 °C(lit.)
| [refractive index ]
n20/D 1.463
| [Fp ]
126 °F
| [pka]
10.89±0.29(Predicted) | [optical activity]
[α]20/D 4°, neat &_& [α]20/D -3.8±0.3°, neat | [Water Solubility ]
Miscible with acetone, chloroform,dimethyl sulfoxide, ethanol, methanol, ether, petroleum ether and dichloromethane. Insoluble in water. | [Sensitive ]
Air Sensitive | [BRN ]
2935070 | [CAS DataBase Reference]
5913-13-3(CAS DataBase Reference) | [NIST Chemistry Reference]
R-(-)-Cyclohexylethylamine(5913-13-3) |
| Safety Data | Back Directory | [Hazard Codes ]
C | [Risk Statements ]
R10:Flammable.
R21/22:Harmful in contact with skin and if swallowed .
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 2734 8/PG 2
| [WGK Germany ]
3
| [F ]
3-10-23 | [HazardClass ]
8 | [PackingGroup ]
II |
| Hazard Information | Back Directory | [Chemical Properties]
optical purity >99% ee | [Uses]
(R)-(-)-1-Cyclohexylethylamine is used in the preparation of benzylidene(1-cyclohexylethyl)amine by reacting with benzaldehyde. It is also used to prepare chiral polymethacrylamides, which are employed as stationary phases for the liquid-chromatographic resolution of racemic amides. In addition to this, it is used in the preparation of polyamides bound to silica gel for high performance liquid chromatography, which are pressure-stable. | [General Description]
(R)-(-)-1-Cyclohexylethylamine is a chiral amine mainly used as a resolving agent for racemic compounds. | [Purification Methods]
Purify it by conversion to the bitartrate salt (m 172o), then decomposing with strong alkali and extracting into Et2O, drying (KOH), filtering, evaporating and distilling. The hydrochloride salt has m 242o (from EtOH/Et2O), [] D -5.0o (c 10 H2O, from (+) amine). The oxalate salt has m 132o (from H2O). The (±)-base has b 176-178o/760mm, and HCl has m 237-238o. [Reihlen et al. Justus Liebigs Ann Chem 532 247 1938, Leithe Chem Ber 65 660 1932, Beilstein 12 III 95.] |
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| Company Name: |
Alfa Aesar
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400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
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