| Identification | More | [Name]
tert-Butyl 1-piperazinecarboxylate | [CAS]
57260-71-6 | [Synonyms]
1-BOC-PIPERAZINE
1-N-BOC-PIPERAZINE
1-(TERT-BUTOXYCARBONYL)PIPERAZINE
BOC-PAZ
BOC-PIPERAZINE
BUTTPARK 52\11-35
N-BOC-PIPERAZINE
N-(T-BOC)PIPERAZINE
N-T-BUTOXYCARBONYLPIPERAZINE
N-(TERT-BUTOXYCARBONYL)PIPERAZINE
N-(TERT-BUTYLOXYCARBONYL)-PIPERAZINE
PIBOC
PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
RARECHEM AR PA 0026
TERT-BUTYL 1-PIPERAZINECARBOXYLATE
TERT-BUTYL N-PIPERAZINE
TERT-BUTYL PIPERAZINE-1-CARBOXYLATE
TERT-BUTYL TETRAHYDROPYRAZINE-1(2H)-CARBOXYLATE
t-Butyl 1-piperazincarboxylate
1-(tert-Butoxycarbonyl)piperazine~tert-Butyl 1-piperazinecarboxylate | [EINECS(EC#)]
611-489-0 | [Molecular Formula]
C9H18N2O2 | [MDL Number]
MFCD00075265 | [Molecular Weight]
186.25 | [MOL File]
57260-71-6.mol |
| Chemical Properties | Back Directory | [Appearance]
Waxy Solid | [Melting point ]
43-47 °C(lit.)
| [Boiling point ]
98-100 | [density ]
1.030±0.06 g/cm3(Predicted) | [Fp ]
>230 °F
| [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [form ]
Low Melting Crystalline Mass | [pka]
8.45±0.10(Predicted) | [color ]
White to light yellow | [Water Solubility ]
Soluble in ethyl acetate, methanol and water. | [Sensitive ]
Air Sensitive | [Detection Methods]
MS,NMR,HPLC | [BRN ]
879985 | [InChIKey]
CWXPZXBSDSIRCS-UHFFFAOYSA-N | [CAS DataBase Reference]
57260-71-6(CAS DataBase Reference) | [NIST Chemistry Reference]
T-butyl 1-piperaziencarboxylate(57260-71-6) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [RIDADR ]
3263 | [WGK Germany ]
3
| [F ]
3-10-34 | [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29335900 |
| Hazard Information | Back Directory | [Chemical Properties]
Waxy Solid | [General Description]
1-Boc-piperazine is an N-Boc protected piperazine. Crosscoupling of 1-Boc-piperazine with aryl iodides using CuBr/1,1′-bi-2-naphthol (catalyst) and K3PO4 (base) has been reported. 1-Boc-piperazine undergoes Buchwald-Hartwig coupling reactions with aryl halides. 1-Boc-piperazine can be prepared in 80% yield via solvent-free N-Boc protection catalyzed by iodine. |
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