| Identification | More | [Name]
Silver acetate | [CAS]
563-63-3 | [Synonyms]
ACETIC ACID SILVER SALT
SILVER ACETATE
SILVER(I) ACETATE
Aceticacid,silver(1+)salt
aceticacid,silver(1++)salt
silver(1+)acetate
silvermonoacetate
Acetic acid silver(I) salt
SILVER ACETATE REAGENTPLUS(TM) 99%
Silver acetate, 99.99% metals basis
SILVER ACETATE, REAGENTPLUS, 99%
Silver acetate, pure, 99%
SILVER ACETATE PURIFIED
Silveracetate,99%
silver acetate, anhydrous
SILVERACETATE,POWDER,PURIFIED
Silver Acetate, powder
Silver acetate, 99%, pure
Acetoxysilver(I) | [EINECS(EC#)]
209-254-9 | [Molecular Formula]
C2H3AgO2 | [MDL Number]
MFCD00012446 | [Molecular Weight]
166.91 | [MOL File]
563-63-3.mol |
| Chemical Properties | Back Directory | [Appearance]
Off-White/Brown Crystalline Powder | [Melting point ]
decomposes [STR93] | [density ]
3.25
| [storage temp. ]
Store below +30°C. | [solubility ]
10.2g/l | [form ]
Powder/Solid | [color ]
White to gray | [Specific Gravity]
3.259 | [Stability:]
Stable, but light sensitive. Incompatible with strong reducing agents. | [Water Solubility ]
10.2 g/L (20 ºC) | [Hydrolytic Sensitivity]
4: no reaction with water under neutral conditions | [Sensitive ]
Light Sensitive | [Merck ]
14,8505 | [BRN ]
3595636 | [Solubility Product Constant (Ksp)]
pKsp: 2.71 | [InChIKey]
CQLFBEKRDQMJLZ-UHFFFAOYSA-M | [CAS DataBase Reference]
563-63-3(CAS DataBase Reference) | [NIST Chemistry Reference]
Silver acetate(563-63-3) | [EPA Substance Registry System]
563-63-3(EPA Substance) |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White/Brown Crystalline Powder | [Uses]
Oxidizing agent for use in liquid ammonia: Kline, Kershner, Inorg. Chem. 5, 932 (1966). | [General Description]
White crystalline plates. Light sensitive. Density 3.26 g /cm3. | [Reactivity Profile]
SILVER ACETATE(563-63-3) is freely soluble in dilute nitric acid [Merck]. Can serve as an oxidizing agent. | [Air & Water Reactions]
Slightly soluble in water. | [Hazard]
Toxic material.
| [Health Hazard]
Inhalation of dust irritates nose and throat. Contact with eyes or skin causes irritation. If continued for a long period, ingestion or inhalation of silver compounds can cause permanent discoloration of skin (argyria). | [Reactions]
3 – 1 - Carbonylation
Silver acetate, when combined with carbon monoxide (CO), can induce the carbonylation of primary and secondary amines. Other silver salts can be used but the acetate gives the best yield.
2 R2NH + 2 AgOAc + CO → [R2N]2CO + 2 HOAc + 2 Ag
3 – 2 - Hydrogenation
Silver acetate in a solution of pyridine absorbs hydrogen and is reduced to metallic silver.
3 – 3 - Direct ortho - arylation
Silver acetate is a useful reagent for direct ortho-arylation (to install two adjacent substituents on an aromatic ring) for of benzylamines and N-methylbenzylamines. The reaction is palladiumcatalized and requires a slight excess of silver acetate.This reaction is shorter than previous ortho-arylation methods. | [Brand name]
Smokerette;Tabmint. | [World Health Organization (WHO)]
Silver acetate has been used as a disinfectant and as an antismoking
aid. It was refused registration in Cyprus on the grounds that prolonged use of silver salts can cause permanent argyria and that no well-controlled trials
have been performed to establish the safety and efficacy of the preparation. It
remains registered as an aid to stopping smoking in Canada and the United States. | [Purification Methods]
Shake it with acetic acid for three days, and the process is repeated with fresh acid. The solid is then dried in a vacuum oven at 40o for 48hours. It has also been recrystallised from water containing a trace of acetic acid, and dried in air. Store it in the dark. [Beilstein 2 IV 112.] | [Safety]
The LD50 of silver acetate in mice is 36.7 mg/kg. Low doses of silver acetate in mice produced hyper-excitability, ataxia, central nervous system depression, labored breathing, and even death. The U.S. FDA recommends that silver acetate intake be limited to 756 mg over a short period of time; excessive intake may cause argyria. | [Synthesis]
The silver acetate salt can be synthesized by the reaction of acetic acid and silver carbonate at 45 – 60 °C. After allowing cooling to room temperature, the solid product precipitates.
2 CH3CO2H + Ag2CO3 → 2 AgO2CCH3 + H2O + CO2
It can also be precipitated from concentrated aqueous solutions of silver nitrate by treatment with a solution of sodium acetate.
The structure of silver acetate consists of 8-membered Ag2O4C2 rings formed by a pair of acetate ligands bridging a pair of silver centres. |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [RIDADR ]
1759 | [WGK Germany ]
3
| [RTECS ]
AJ4100000
| [F ]
8 | [TSCA ]
Yes | [HazardClass ]
9 | [HS Code ]
28432900 |
| Questions And Answer | Back Directory | [Description]
Silver acetate (C2H3AgO2) is a photosensitive, white, crystalline solid which is widely used in the laboratory. As a source of silver ions lacking an oxidizing anion, it is a useful reagent for direct ortho-arylation, and for conversion of organohalogen compounds into alcohols, etc. It also serves as a catalyst to effectively catalyze the cycloaddition reactions of isocyanoacetates with a variety of olefins. It can be employed in the novel preparation of highly reflective, conductive silvered polymer films.Besides, it has applications in some antismoking drugs and in the health field, in which the products containing silver acetate have been applied in spray, and lozenges to deter smokers from smoking. When mixed with smoke, the silver acetate creates an unpleasant metallic taste in the smoker's mouth, thereby preventing them from smoking.
| [References]
https://en.wikipedia.org/wiki/Silver_acetate
https://www.alfa.com/zh-cn/catalog/011660/
http://www.sigmaaldrich.com/catalog/product/sigma/s1633?lang=en®ion=US
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