Identification | More | [Name]
Arprinocide | [CAS]
55779-18-5 | [Synonyms]
9-[(2-CHLORO-6-FLUOROPHENYL)METHYL]-9H-PURIN-6-AMINE ARPRINOCID arprinocide 9-[(2-Chloro-6-fluorophenyl)methyl]-9H-purine-6-amine Arpronocid 9-[(2-Chloro-6-fluorophenyl)methyl]purin-6-amine 6-Amino-9-(2-chloro-6-fluorobenzyl)purine 9H-Purin-6-amine, 9-[(2-chloro-6-fluorophenyl)methyl]- Arpocox MK-302 | [EINECS(EC#)]
259-817-8 | [Molecular Formula]
C12H9ClFN5 | [MDL Number]
MFCD00867210 | [Molecular Weight]
277.68 | [MOL File]
55779-18-5.mol |
Chemical Properties | Back Directory | [Melting point ]
245-246° | [Boiling point ]
504.6±60.0 °C(Predicted) | [density ]
1.568 g/cm3 | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
3.91±0.10(Predicted) | [color ]
Pale Yellow to Pale Beige | [λmax]
260nm(NaOH aq.)(lit.) | [CAS DataBase Reference]
55779-18-5(CAS DataBase Reference) |
Hazard Information | Back Directory | [Chemical Properties]
Pale Yellow Solid | [Originator]
Arprinocid,NANJING PHARMA | [Uses]
Arprinocide can be used as a Coccidiostat used in veterinary medicine.
| [Definition]
ChEBI: Arprinocid is a member of 6-aminopurines. | [Manufacturing Process]
To a solution of potassium t-butoxide in absolute ethanol slowly adding dry
adenine. This mixture was stirred for about 2 h, and then 2-chloro-6-
fluorobenzyl chloride was added over a period of about 4 h. The resulting
mixture was heated to reflux with stirring and allowed to react for about 42 h,
after which it was cooled to about 10°C. The crude product thus formed was
isolated by filtration and then washed with ice cold ethanol and ice cold water
to yield a 6-amino-9-(2-chloro-6-fluorobenzyl)purine. | [Brand name]
Arpocox (Merck). | [Therapeutic Function]
Coccidiostatic | [Synthesis Reference(s)]
The Journal of Organic Chemistry, 43, p. 960, 1978 DOI: 10.1021/jo00399a034 |
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TCI AMERICA
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