| Identification | More | [Name]
Phenyl vinyl sulfone | [CAS]
5535-48-8 | [Synonyms]
PHENYL VINYL SULFONE
PHENYL VINYL SULPHONE
PHENYLVINYLSULTONE
VINYL PHENYL SULFONE
(Vinylsulfonyl)benzene
Sulfone, phenyl vinyl
URI 744
Eletriptan intermediate 1
Phenylvinylsulfone,99+%
Benzene, (ethenylsulfonyl)-
Phenyl vinyl sulphone, 99+%
1-(Phenylsulfonyl)ethene | [EINECS(EC#)]
226-890-2 | [Molecular Formula]
C8H8O2S | [MDL Number]
MFCD00007554 | [Molecular Weight]
168.21 | [MOL File]
5535-48-8.mol |
| Chemical Properties | Back Directory | [Appearance]
off-white or tan powder | [Melting point ]
67-69 °C (lit.) | [Boiling point ]
267.16°C (rough estimate) | [density ]
1.2660 (rough estimate) | [refractive index ]
1.5090 (estimate) | [storage temp. ]
Refrigerator (+4°C) | [solubility ]
It is soluble in most common organic solvents. | [form ]
Solid | [color ]
White | [Stability:]
Stable. Incompatible with strong oxidizing agents. | [BRN ]
1906894 | [InChIKey]
UJTPZISIAWDGFF-UHFFFAOYSA-N | [CAS DataBase Reference]
5535-48-8(CAS DataBase Reference) | [NIST Chemistry Reference]
Benzene, (ethenylsulfonyl)-(5535-48-8) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R43:May cause sensitization by skin contact. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [HS Code ]
29309090 |
| Hazard Information | Back Directory | [Chemical Properties]
off-white or tan powder | [Uses]
As common reagent, Phenyl vinyl sulfone is used in a variety of cycloaddition reactions to form cyclopropanes,1 cyclohexenes,2,3 and cyclooctadienes.
| [Uses]
Phenyl Vinyl Sulfone is a synthetic inhibitor of cysteine protease and has antihelminthic and antiprotozoal properties. Phenyl Vinyl Sulfone is also an inhibitor of transpeptidase SrtA required for cell wall protein anchoring and virulence in Staphylococcus aureus. | [Synthesis Reference(s)]
The Journal of Organic Chemistry, 48, p. 4976, 1983 DOI: 10.1021/jo00173a039 | [General Description]
Phenyl vinyl sulfone, a synthetic inhibitor of cysteine protease, exhibits antihelminthic and antiprotozoal properties. |
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