| Identification | More | [Name]
2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid | [CAS]
4065-45-6 | [Synonyms]
2-Benzoyl-5-methoxy-1-phenol-4-sulfonic acid
2-HYDROXY-4-METHOXY-5-SULFOBENZOPHENONE
2-HYDROXY-4-METHOXY-5-SULFONYLBENZOPHENONE
2-HYDROXY-4-METHOXYBENZOPHENONE-5-SULFONIC ACID
2-HYDROXY-4-METHOXYBENZOPHENONE-5-SULFONIC ACID HYDRATE
2-HYDROXY-4-METHOXYBENZOPHENONE-5-SULPHONIC ACID
5-BENZOYL-4-HYDROXY-2-METHOXYBENZENESULFONIC ACID
BENZOPHENONE-4
BP-4
HMBS
spectra-sorb uv 284
SULISOBENZONE
TIMTEC-BB SBB002961
UV ABSORBER HMBS
Uvistat 1121
2-benzoyl-5-methoxy-1-phenol-4-sulfonicaci
2-Hydroxy-4-Methoxy-5-Benzophenonesulfonicacid
5-benzoyl-4-hydroxy-2-methoxy-benzenesulfonicaci
Benzenesulfonicacid,5-benzoyl-4-hydroxy-2-methoxy-
Benzophenone-4,sulisobenzone | [EINECS(EC#)]
223-772-2 | [Molecular Formula]
C14H12O6S | [MDL Number]
MFCD00024962 | [Molecular Weight]
308.31 | [MOL File]
4065-45-6.mol |
| Chemical Properties | Back Directory | [Appearance]
white to yellowish powder | [Melting point ]
170 °C
| [Boiling point ]
0°C | [density ]
1.4574 (rough estimate) | [vapor pressure ]
0Pa at 25℃ | [refractive index ]
1.5300 (estimate) | [Fp ]
0°C | [storage temp. ]
-20°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
neat | [pka]
-0.70±0.50(Predicted) | [color ]
White to Off-White | [Water Solubility ]
300.92g/L at 25℃ | [Merck ]
14,8983 | [BRN ]
2889165 | [Contact allergens]
BZP-4 is widely used in cosmetics, particularly shampoos
and hair products. Cross-reactivity is rarely
expected in patients photoallergic to ketoprofen. | [InChIKey]
CXVGEDCSTKKODG-UHFFFAOYSA-N | [LogP]
0.515 at 25℃ | [Uses]
benzophenone-4 (sulisobenzone) is a commonly used, FDAapproved sunscreen chemical with uVA-absorbing properties and an approved usage level of 5 to 10 percent. It protects a formulation from the effects of uV-light exposure. | [CAS DataBase Reference]
4065-45-6(CAS DataBase Reference) | [EPA Substance Registry System]
4065-45-6(EPA Substance) |
| Hazard Information | Back Directory | [Chemical Properties]
white to yellowish powder | [Uses]
ultraviolet screen | [Uses]
Ultraviolet absorber for leather and textile fibers; in cosmetics and shampoos. | [Originator]
Uval,Dome,US,1965 | [Definition]
ChEBI: Sulisobenzone is a member of benzophenones. | [Manufacturing Process]
663 g of dichloroethane and 74.6 g 2-hydroxy-4-methoxybenzophenone were charged into a 3-neck flask equipped with stirrer, thermometer, reflux
condenser and dropping funnel and a heating mantle. The solution was heated
to the reflux temperature (85°C to 86°C) and was dehydrated by distilling off
66.5 g 1,2-dichloroethane. While maintaining at reflux, 30 g chlorosulfonic
acid was added slowly over a period of about two hours. The rate of addition
was regulated by the speed of evolution of the HCl. After all the chlorosulfonic
acid was added, the charge was still maintained at reflux for an additional 15
minutes to remove traces of HCl. It was then cooled to 5°C and filtered. The
filter cake was washed with 500 g cold 1,2-dichloroethane and dried. 98 g of
product were obtained. | [Brand name]
Sungard (Bayer). | [Therapeutic Function]
Sunscreen agent | [General Description]
Sulisobenzone is a broad spectrum organic UV filter in sunscreen formulations, known to absorb deleterious UV light. | [Flammability and Explosibility]
Nonflammable | [storage]
Store at -20°C |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S27:Take off immediately all contaminated clothing . | [WGK Germany ]
1
| [RTECS ]
DB5044300
| [TSCA ]
Yes | [HS Code ]
29144000 | [Hazardous Substances Data]
4065-45-6(Hazardous Substances Data) |
|
|