| Identification | More | [Name]
Trifluoroacetamidine | [CAS]
354-37-0 | [Synonyms]
TRIFLUOROACETAMIDINE, TECH.
Trifluoroacetamidine | [EINECS(EC#)]
670-531-6 | [Molecular Formula]
C2H3F3N2 | [MDL Number]
MFCD00041545 | [Molecular Weight]
112.05 | [MOL File]
354-37-0.mol |
| Chemical Properties | Back Directory | [Boiling point ]
35-37°C 11mm | [density ]
1.45 | [refractive index ]
1.3801 | [Fp ]
35-37°C/11mm | [storage temp. ]
Store below-20C | [form ]
liquid | [pka]
6.07±0.40(Predicted) | [color ]
Clear, yellow | [Water Solubility ]
Fully miscible in water. | [Sensitive ]
Moisture Sensitive | [BRN ]
605978 | [InChI]
InChI=1S/C2H3F3N2/c3-2(4,5)1(6)7/h(H3,6,7) | [InChIKey]
NITMACBPVVUGOJ-UHFFFAOYSA-N | [SMILES]
C(N)(=N)C(F)(F)F | [CAS DataBase Reference]
354-37-0(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
C,Xi | [Risk Statements ]
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [RIDADR ]
3267 | [Hazard Note ]
Corrosive/Irritant | [HazardClass ]
8 | [PackingGroup ]
II | [HS Code ]
29252900 |
| Hazard Information | Back Directory | [Chemical Properties]
Colorless liquid | [Uses]
Trifluoroacetamidine is used as probe for determination of membrane potential and extra/intracellular volume of erythrocytes by fluorine-19 NMR studies. It is a reagent used as protected ammonia equivalent. | [Synthesis]
Trifluoroacetamidine is a vital chemical intermediate with a wide range of applications. A preparation method comprises the following steps: trifluoroacetamide is used as raw materials, polyphosphoric acid is selected as solvents under the effect of phosphorus pentoxide as dehydrating agents, and trifluoroacetonitrile can be fast prepared through a dehydration reaction. The generated trifluoroacetonitrile gas is introduced into a liquid ammonia kettle after being cooled, and the trifluoroacetamidine can be prepared. |
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