| Identification | More | [Name]
2-Amino-6-fluorobenzothiazole | [CAS]
348-40-3 | [Synonyms]
2-AMINO-6-FLUOROBENZOTHIAZOLE
6-FLUORO-1,3-BENZOTHIAZOL-2-AMINE
6-FLUORO-2-BENZOTHIAZOLAMINE
6-FLUOROBENZO[D]THIAZOL-2-AMINE
6-FLUORO-BENZOTHIAZOL-2-YLAMINE
AKOS B034895
AKOS BB-8275
ASISCHEM Y86622
OTAVA-BB BB7110950332
TIMTEC-BB SBB000158
2-Amino-6-fluorobenzo-1,3-thiazole
2-Amino-6-Fluorolbenzothiazole
2-Amino-6-fluorobenzo-1,3-thiazole 99%
2-Amino-6-fluorobenzo-1,3-thiazole99%
2-Benzothiazolamine,6-fluoro-(9CI) | [EINECS(EC#)]
609-034-6 | [Molecular Formula]
C7H5FN2S | [MDL Number]
MFCD00013336 | [Molecular Weight]
168.19 | [MOL File]
348-40-3.mol |
| Chemical Properties | Back Directory | [Appearance]
off-white to tan crystalline powder | [Melting point ]
183-185 °C (lit.) | [Boiling point ]
312.0±34.0 °C(Predicted) | [density ]
1.3490 (estimate) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Crystalline Powder | [pka]
3.77±0.10(Predicted) | [color ]
Off-white to tan | [InChI]
InChI=1S/C7H5FN2S/c8-4-1-2-5-6(3-4)11-7(9)10-5/h1-3H,(H2,9,10) | [InChIKey]
CJLUXPZQUXVJNF-UHFFFAOYSA-N | [SMILES]
S1C2=CC(F)=CC=C2N=C1N | [CAS DataBase Reference]
348-40-3(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R22:Harmful if swallowed. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29342000 |
| Questions And Answer | Back Directory | [Structure]
Crystals of 2-amino-6-fluoro-1,3-benzothiazole, C7H5FN2S, have an amphiphilic layer-like structure. Each amino substituent donates two protons to hydrogen bonds and accepts one. The ring N atoms accept one proton. The F atoms are not involved in any hydrogen bonds. |
| Hazard Information | Back Directory | [Chemical Properties]
off-white to tan crystalline powder | [Uses]
2-Amino-6-fluorobenzothiazole is a useful research chemical. An intermediate for the synthesis of benzothiazoles and aminobenzothiazoles with antimicrobial activity. | [Application]
2-Amino-6-fluorobenzothiazole (AFBT) can be used for:
(1) Interaction of AFBT with β-cyclodextrin (β-CDx) in aqueous and solid state. The proton transfer behaviour of AFBT in aqueous and β-CDx solutions was studied.
(2) Spectroscopic studies. Fourier transform infrared spectroscopy (4000-400 cm-1) and Fourier transform Raman spectroscopy (4000-100 cm-1) measurements were carried out on AFBT to investigate the effect of fluorine and amino groups on the backbone pattern and proton chemical shifts. | [Definition]
ChEBI: 6-Fluoro-1,3-benzothiazol-2-amine is a member of benzothiazoles. |
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