| Identification | More | [Name]
DL-Adrenalin | [CAS]
329-65-7 | [Synonyms]
1-(3,4-dihydroxyphenyl)-2-(methylamino)ethanol
3,4-dihydroxy-1-[1-hydroxy-2-(methylamino)-ethyl]benzene
3,4-DIHYDROXY-ALPHA-(METHYLAMINOMETHYL)BENZYL ALCOHOL
4-[1-HYDROXY-2-(METHYLAMINO)ETHYL]-1,2-BENZENEDIOL
4-(1-HYDROXY-2-METHYLAMINO-ETHYL)-BENZENE-1,2-DIOL
(+/-)-ADRENALIN
dl-adrenalin
DL-ADRENALINE
DL-EPINEPHRINE
(+/-)-EPINEPHRINE
RACEPINEPHRINE
4-(1-hydroxy-2-(methylamino)ethyl)-2-benzenedio(+-)-
4-dihydroxy-alpha-((methylamino)methyl)-(+-)-benzylalcoho
epinephrineracemic
epirenamine
racepinefrine
(+-)-EPINEPHRINE APPROX. 95%
DL-EPINEPHRINE (DL-ADRENALINE)
DL-ADRENALINE(1-3,4-DIHYDROXY-ALPHA[(METHYL-AMINO)METHYL]BENZYLALCOHOL)
3,4-dihydroxy-α-(methylaminomethyl)-benzyl alcohol | [EINECS(EC#)]
206-347-6 | [Molecular Formula]
C9H13NO3 | [MDL Number]
MFCD00063027 | [Molecular Weight]
183.2 | [MOL File]
329-65-7.mol |
| Chemical Properties | Back Directory | [Appearance]
Solid | [Melting point ]
197 °C (dec.)(lit.)
| [alpha ]
-0.5～+0.5°(D/20)(c=1,0.1mol/l HCl) | [Boiling point ]
316.88°C (rough estimate) | [density ]
1.1967 (rough estimate) | [refractive index ]
1.4760 (estimate) | [storage temp. ]
2-8°C
| [solubility ]
0.1 M HCL : 2.5 mg/mL (13.65 mM; ultrasonic and adjust pH to 1 with HCl)DMSO : 1 mg/mL (5.46 mM; ultrasonic and adjust pH to 7 with HCl)Ethanol : < 1 mg/mL (insoluble)H2O : < 0.1 mg/mL (insoluble) | [form ]
Powder | [pka]
9.60±0.10(Predicted) | [Water Solubility ]
Sparingly soluble | [Sensitive ]
Light Sensitive | [Merck ]
3619 | [CAS DataBase Reference]
329-65-7(CAS DataBase Reference) | [EPA Substance Registry System]
329-65-7(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
T | [Risk Statements ]
R24:Toxic in contact with skin.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 2811 6.1/PG 2
| [WGK Germany ]
3
| [RTECS ]
DO2975000
| [HazardClass ]
6.1(b) | [PackingGroup ]
III |
| Hazard Information | Back Directory | [General Description]
Odorless light brown or nearly white crystals. | [Reactivity Profile]
Light sensitive. Incompatible with heat, air, iron salts, and alkalis. . An aminoalcohol. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Incompatible with heat, air, iron salts, and alkalis. . | [Air & Water Reactions]
Slightly water soluble . | [Health Hazard]
SYMPTOMS: Pallor, tremor, anxiety, nervousness, rapid, forceful pulse, rise in blood pressure and temperature, rapid breathing, dilation of the pupils. | [Fire Hazard]
Flash point data for this compound are not available, however, 3,4-DIHYDROXYL-ALPHA-[METHYLAMINO]METHYLBENZYL ALCOHOL is probably combustible. | [Chemical Properties]
Solid | [Uses]
DL-Adrenaline is a hormone and a neurotransmitter secreted by the medulla of the adrenal glands. In medicine DL-Adrenaline is used chiefly as a stimulant in cardiac arrest, as a vasoconstrictor in shock, and as a bronchodilator and antispasmodic in bronch | [Uses]
Endogenous catcholamine with combined α-and β-agonist activity. Principal sympathomimetic hormone produced by the adrenal medulla. Bronchodilator; cardiostimulant; mydriatic; antiglaucoma. | [Definition]
ChEBI: A catecholamine in which the aminoethyl side-chain is hydroxy-substituted at C-1 and methylated on nitrogen. | [Brand name]
Vaponefrin (Fisons). | [storage]
Store at -20°C |
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