| Identification | More | [Name]
2,2-DIPHENYLGLYCINE | [CAS]
3060-50-2 | [Synonyms]
2,2-DIPHENYLGLYCINE
A,A-DIPHENYLGLYCINE
ALPHA,ALPHA-DIPHENYLGLYCINE
AMINODIPHENYLACETIC ACID
DIPHENYLGLYCIN
LABOTEST-BB LT00159592
2,2-diphenyl-glycin
alpha-amino-alpha-phenylbenzeneaceticacid
alpha-aminodiphenylaceticacid
alpa,alpha-Diphenylglycine | [EINECS(EC#)]
221-299-6 | [Molecular Formula]
C14H13NO2 | [MDL Number]
MFCD00008048 | [Molecular Weight]
227.26 | [MOL File]
3060-50-2.mol |
| Chemical Properties | Back Directory | [Appearance]
white powder | [Melting point ]
245-247 °C (dec.) (lit.) | [Boiling point ]
368.97°C (rough estimate) | [density ]
1.231±0.06 g/cm3 (20 ºC 760 Torr) | [refractive index ]
1.5780 (estimate) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
DMSO (Slightly, Heated), Methanol (Slightly, Heated) | [form ]
Powder | [pka]
1.38±0.10(Predicted) | [color ]
White | [Water Solubility ]
It is sparingly soluble in water. | [Stability:]
Hygroscopic | [InChIKey]
YBONNYNNFBAKLI-UHFFFAOYSA-N | [CAS DataBase Reference]
3060-50-2(CAS DataBase Reference) |
| Safety Data | Back Directory | [Safety Statements ]
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [RTECS ]
MC0176000
| [HS Code ]
29224999 |
| Questions and Answers (Q&A) | Back Directory | [Description]
2, 2-Diphenylglycine is a highly similar analogue and the simplest aromatic peptide. It can be used as a synthesis reagent for amination reactions. It is a useful intermediate in pharmaceutical and in organic synthesis. Its derivatives have been also be shown to exhibit anticonvulsants activity and can be used for the treatment of pain.
| [References]
And, Meital Reches, and E. Gazit. "Formation of Closed-Cage Nanostructures by Self-Assembly of Aromatic Dipeptides." Nano Letters 4.4(2006):581-585.
https://www.alfa.com/en/catalog/B22650/
Harris, Robert H. "New uses for amino acid anticonvulsants for treatment of pain." EP, WO/2002/015922. 2002.
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| Hazard Information | Back Directory | [Chemical Properties]
white powder | [Uses]
2,2-Diphenylglycine is used as a synthesis reagent for amination reactions. It acts as an intermediate in pharmaceutical and in organic synthesis. | [reaction suitability]
reaction type: solution phase peptide synthesis |
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