| Identification | More | [Name]
Aminoguanidine bicarbonate | [CAS]
2582-30-1 | [Synonyms]
1-AMINOGUANIDINE BICARBONATE
1-AMINOGUANIDINE HYDROGEN CARBONATE
1-AMINOGUANIDINIUM HYDROGEN CARBONATE
AMINOGUANADINE BICARBONATE
AMINOGUANIDINE BICARBONATE
AMINOGUANIDINE BICARBONATE SALT
AMINOGUANIDINE CARBONIC ACID
AMINOGUANIDINE HYDROGEN CARBONATE
aminoguanidinium hydrogen carbonate
GUANYLHYDRAZINE BICARBONATE
GUANYLHYDRAZINE HYDROGENCARBONATE
LABOTEST-BB LTBB000461
Aminoguanidine bicarbonate
Aminoguanidine hydrogen carbonate
AMINOGUANIDINE BICARBONATE CRYSTALLINE
1-AMINOGUANIDINIUM HYDROGEN CARBONATE OE
Aminoguanidine bicarbonate, 98.50%
Carbonic acid, compd. with hydrazinecarboximidamide (1:1)
guanylhydrazine bicarbonate salt
CARBONICACID,COMPDWITHHYDRAZINECARBOXIMIDAMIDE
Aminoguanidinbicarbonat | [EINECS(EC#)]
219-956-7 | [Molecular Formula]
C2H8N4O3 | [MDL Number]
MFCD00012949 | [Molecular Weight]
136.11 | [MOL File]
2582-30-1.mol |
| Chemical Properties | Back Directory | [Appearance]
White to off-white crystalline powder | [Melting point ]
170-172 °C (dec.)(lit.)
| [density ]
1,6 g/cm3 | [storage temp. ]
Store below +30°C. | [solubility ]
H2O: soluble2.7g/L at 20°C | [form ]
Crystalline Powder | [pka]
6.19[at 20 ℃] | [color ]
White to off-white | [PH]
8.9 (5g/l, H2O, 20℃) | [Water Solubility ]
<5 g/L (20 ºC) | [BRN ]
3569869 | [InChI]
InChI=1S/CH6N4.CH2O3/c2-1(3)5-4;2-1(3)4/h4H2,(H4,2,3,5);(H2,2,3,4) | [InChIKey]
OTXHZHQQWQTQMW-UHFFFAOYSA-N | [SMILES]
N(N)C(=N)N.C(O)(=O)O | [LogP]
-6.61 at 25℃ | [CAS DataBase Reference]
2582-30-1(CAS DataBase Reference) | [EPA Substance Registry System]
2582-30-1(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R52/53:Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
R43:May cause sensitization by skin contact.
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S37:Wear suitable gloves .
S24:Avoid contact with skin .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [RIDADR ]
UN3077 | [WGK Germany ]
2
| [RTECS ]
FG1772000
| [Autoignition Temperature]
245 °C | [TSCA ]
Yes | [HazardClass ]
9 | [PackingGroup ]
III | [HS Code ]
29280090 | [Toxicity]
LD50 orally in Rabbit: > 5000 mg/kg |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
Hydrazinium hydroxide solution-->Ammonium bicarbonate-->2-Methyl-2-thiopseudourea sulfate-->Hydrazine sulfate-->Calcium cyanamide-->Cyanamide-->Calcium oxalate-->Nitroguanidine | [Preparation Products]
7-BROMO-3-TRIFLUOROMETHYL-IMIDAZO[1,2-B][1,2,4]TRIAZINE-->METOSULAM-->3-Amino-1,2,4-Triazole-->Mitoguazone-->pimagedine-->2-(2,3-Dichlorophenyl)-2-guanidinyliminoacetonitrile-->GUANABENZ ACETATE-->5-METHYL-[1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-2-YLAMINE-->1H-Pyrazole-1-carboximidamide,2,5-dihydro-4-(2-hydroxyethyl)-3-methyl-5-oxo-(9CI)-->2H-Indazole-2-carboximidamide,1,3,4,5,6,7-hexahydro-3-oxo-(9CI)-->OXALYL MONOGUANYLHYDRAZIDE-->4H-Cyclopentapyrimidin-4-one, 2,3-diamino-3,5,6,7-tetrahydro- (9CI) |
| Hazard Information | Back Directory | [Chemical Properties]
White to off-white crystalline powder | [Uses]
Aminoguanidinium Bicarbonate is used in the synthesis of antitumor agents and antileukemic activity. Also used in the synthesis of neuraminidase inhibitors in the inhibition of influenze. | [Application]
Aminoguanidine bicarbonate is an inhibitor of NOS (nitric oxide synthase). Aminoguanidine bicarbonate is used to study the effect of addition of polyamines to rat embryo cell cultures infected with adenovirus type 5. | [Flammability and Explosibility]
Nonflammable | [Biochem/physiol Actions]
Aminoguanidine bicarbonate protects the cells infected with adenovirus from chromosomal damage. Aminoguanidine is a specific and highly effective inhibitor of diamine oxidase present in fetal calf serum. | [Synthesis]
A synthesis method of aminoguanidine bicarbonate includes reacting an acidic aqueous hydrazine hydrate solution with calcium cyanamide in an elevated temperature to produce an aminoguanidine solution, recovering the solution, and reacting therewith an alkali metal bicarbonate to produce relatively high purity aminoguanidine bicarbonate. | [storage]
+4°C |
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