| Identification | More | [Name]
3-AMINOPROPIONITRILE FUMARATE | [CAS]
2079-89-2 | [Synonyms]
3-AMINOPROPIONITRILE FUMARATE
3-AMINOPROPIONITRILE FUMARATE SALT
BETA-AMINOPROPIONITRILE MONOFUMARATE
BETA-AMINOPROPIONITRILE MONOFUMARATE SALT
BIS-(3-AMINOPROPIONITRILE) FUMARATE
TIMTEC-BB SBB008547
3-amino-propanenitril(e)-2-butenedioate(2:1)
3-amino-propionitrilfumarate(2:1)
beta-aminopropionitrile,fumarate
di-beta-aminopropionitrilefumarate
2-Cyanoethylamine hemifumarate
3-Aminopionitrile Fumarate
B-aminopropionitrile monofumarate
di(2-cyanoethylammonium) fumarate
bis(3-aminopropiononitrile) fumarate
3-AMINOPROPIONITRILE FUMARATE, 99+%
3-AMINOPROPIONITRILE FUMARATE (BETA-) 98+%
Bis-(3-aminopropionitrile) fumarate, 99+%
3-Aminopropionitrile fumarate, 98+%
3-Aminopropionitrile/fumaric acid,(2:1) | [EINECS(EC#)]
218-208-7 | [Molecular Formula]
C7H10N2O4 | [MDL Number]
MFCD00078321 | [Molecular Weight]
186.17 | [MOL File]
2079-89-2.mol |
| Safety Data | Back Directory | [Hazard Codes ]
T | [Risk Statements ]
R61:May cause harm to the unborn child. | [Safety Statements ]
S53:Avoid exposure-obtain special instruction before use .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [WGK Germany ]
3
| [RTECS ]
UG0700000
| [TSCA ]
Yes | [HS Code ]
29269095 | [Safety Profile]
Moderately toxic by ingestion and intraperitoneal routes. An experimental teratogen. When heated to decomposition it emits toxic fumes of NO, and CN-. See also NITRILES. | [Toxicity]
LDLo orl-rat: 800 mg/kg TJADAB 5,33,72 |
| Hazard Information | Back Directory | [Chemical Properties]
WHITE CRYSTALLINE POWDER | [Uses]
3-Aminopropionitrile fumarate salt has been used as a lysyl oxidase (LOX) inhibitor:
- to inhibit collagen cross-linking during microtissue formation and culture
- in LIM domain only 1 (LMO1)- or vector-expressing BE2C neuroblastoma cell line in transwell migration and invasion assay
- in lysyl oxidase (LOX) activity assay
- to study requirement of LOX activity for inducing hypoxia-inducible factor (HIF)2A-dependent stiffness in mouse organoids
| [Definition]
ChEBI: A fumarate salt prepared from beta-aminopropionitrile by reaction of one molecule of fumaric acid for every two molecules of beta-aminopropionitrile. | [Biochem/physiol Actions]
3-Aminopropionitrile (β-Aminopropionitrile (BAPN)) functions as an irreversible inhibitor of lysyl oxidase (LOX), an enzyme involved in collagen cross-linking. |
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