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ChemicalBook--->CAS DataBase List--->17737-65-4

17737-65-4

17737-65-4 Structure

17737-65-4 Structure
IdentificationMore
[Name]

Clonixin
[CAS]

17737-65-4
[Synonyms]

2-[(3-chloro-2-methylphenyl)amino]-3-pyridinecarboxylic acid
CLONIXIC ACID
CLONIXIN
3-Pyridinecarboxylic acid, 2-[(3-chloro-2-methylphenyl)amino]-
CLONIXIC ACID (CLONIXIN)
2-(3-CHLORO-2-METHYLPHENYLAMINO)NICOTINIC ACID
2-(3-Chloro-2-methylanilino)pyridine-3-carboxylic acid
2-(3-Chloro-o-toluidino)nicotinic acid
Sch-10304
[EINECS(EC#)]

241-730-1
[Molecular Formula]

C13H11ClN2O2
[MDL Number]

MFCD00864292
[Molecular Weight]

262.69
[MOL File]

17737-65-4.mol
Chemical PropertiesBack Directory
[Melting point ]

233-235°
[Boiling point ]

410.2±45.0 °C(Predicted)
[density ]

1.3230 (rough estimate)
[refractive index ]

1.5270 (estimate)
[storage temp. ]

Keep in dark place,Inert atmosphere,Room temperature
[solubility ]

DMSO: soluble15mg/mL, clear
[form ]

powder
[pka]

1.69±0.36(Predicted)
[color ]

white to beige
[Merck ]

14,2392
[CAS DataBase Reference]

17737-65-4(CAS DataBase Reference)
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

20/21/22
[Safety Statements ]

36/37
[WGK Germany ]

3
[RTECS ]

QT0960000
[HS Code ]

2933.39.9200
[Toxicity]

LD50 in male mice, rats (mg/kg): 415, 335 orally; 198, 148 i.p.; 296, 325 s.c. (Tanaka)
Hazard InformationBack Directory
[Uses]

Analgesic.
[Uses]

Clonixin is a non-steroidal anti-inflammatory drug. It also has analgesic, antipyretic, and platelet-inhibitory actions. The compound has been reported to block prostaglandin synthesis, and to block inward calcium currents.
[Definition]

ChEBI: A pyridinemonocarboxylic acid that is nicotinic acid substituted at position 2 by a (2-methyl-3-chlorophenyl)amino group. Used (as its lysine salt) for treatment of renal colic, muscular pain and moderately severe migraine attacks.
Spectrum DetailBack Directory
[Spectrum Detail]

Clonixin(17737-65-4)1HNMR
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