Identification | More | [Name]
8-Bromoquinoline | [CAS]
16567-18-3 | [Synonyms]
8-BROMOQUINOLINE RARECHEM AK ML 0146 8-BROMOQUIOLINE http://www.ruiyitech.com/detail.phpCAS=578-66-5&class_id=4 8-bromooquinoline 8-Bromoquinoline ,97% | [EINECS(EC#)]
630-629-1 | [Molecular Formula]
C9H6BrN | [MDL Number]
MFCD00191859 | [Molecular Weight]
208.05 | [MOL File]
16567-18-3.mol |
Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powder | [Melting point ]
58-59 °C
| [Boiling point ]
112-113 °C/0.5 mmHg (lit.) | [density ]
1.594 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.672(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
Refrigerator (+4°C) | [form ]
Liquid After Melting | [pka]
2.33±0.17(Predicted) | [color ]
Clear yellow to yellow-brown | [Specific Gravity]
1.594 | [Sensitive ]
Light Sensitive | [Detection Methods]
GC | [InChIKey]
PIWNKSHCLTZKSZ-UHFFFAOYSA-N | [CAS DataBase Reference]
16567-18-3(CAS DataBase Reference) | [NIST Chemistry Reference]
Quinoline, 8-bromo-(16567-18-3) | [Storage Precautions]
Store under nitrogen |
Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36:Wear suitable protective clothing . S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HS Code ]
29334900 |
Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powder | [Uses]
8-Bromoquinoline may be used in the following studies:
- Synthesis of 8-(dimesitylboryl)quinolone (ambiphilic molecule).
- Direct synthesis of 5H-pyrido[3,2,1-ij]quinolin-3-one, via palladium catalyzed coupling reaction with acrolein.
- Preparation of 8-(1-hydroxyethyl)quinolone.
- Preparation of 8-quinolylcyclopentadienyl metal complexes, via reaction with zincated cyclopentadienyl derivatives of Fe, Mn and Re in the presence of bis(triphenylphosphine)palladium(0).
- Synthesis of n,n′-biquinolines by a coupling reaction using tris(triphenylphosphine)nickel(0) and a zerovalent pyridine-nickel complex.
| [General Description]
8-Bromoquinoline is a quinolone derivative. It is widely employed for the synthesis of dyes, food colors, pharmaceutical reagents, pH indicators and in various industrial processes. Its molecule bears a pyridyl group. It undergoes direct heteroarylation reaction with various heteroaromatic compounds in the presence of a palladium catalyst to afford polyheteroaromatic derivatives. |
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