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ChemicalBook--->CAS DataBase List--->163759-97-5

163759-97-5

163759-97-5 Structure

163759-97-5 Structure
IdentificationBack Directory
[Name]

(2R,3R,4R,5R)-2-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)-5-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)-4-(2-METHOXYETHOXY)TETRAHYDROFURAN-3-YL 2-CYANOETHYL DIISOPROPYLPHOSPHORAMIDITE
[CAS]

163759-97-5
[Synonyms]

2'-O-MOE-U Phosphoramidite
2'-O-MOE-rU Phosphoramidite
2'-O-MOE-U-CE Phosphoramidite
2'-O-MOE-U-3'-phosphoramidite
DMT-2'-O-MOE-U-CE-Phosphoramidite
5'-O-DMT-2'-(2-methoxyethyl)uridine 3'-CE phosphoramidite
5'-O-DMT-2'-O-(2-methoxyethyl)uridine 3'-CE phosphoramidite
5'-O-DMTr-2'-O-(2-methoxyethyl)-uridine-3'-CED-phosphoramidite
5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-uridine-3'-cyanoethyl Phosphoramidite
5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)uridine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]
Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI)
(2R,3R,4R,5R)-2-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)-5-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)-4-(2-METHOXYETHOXY)TETRAHYDROFURAN-3-YL 2-CYANOETHYL DIISOPROPYLPHOSPHORAMIDITE
[Molecular Formula]

C42H53N4O10P
[MDL Number]

MFCD11505866
[MOL File]

163759-97-5.mol
[Molecular Weight]

804.86
Chemical PropertiesBack Directory
[storage temp. ]

4°C, protect from light
[form ]

Solid
[pka]

9.39±0.10(Predicted)
[color ]

White to off-white
[InChIKey]

ZLOKLUONKGURQI-LWTSSKLSNA-N
[SMILES]

O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@H](OCCOC)[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,36,42,r|
Hazard InformationBack Directory
[Description]

2'-O-MOE-U-3'-phosphoramidite (DMT-2'-O-MOE-rU Phosphoramidite) is a 2'-O-MOE-protected nucleoside phosphoramidite that can be inserted into oligonucleotide phosphoramidites for antisense RNA. The 2'-MOE backbone enhances stability, resists nuclease, and exhibits low toxicity for improved genetic manipulation.
[Chemical Properties]

White to Light yellow powder to crystal
[storage]

4°C, protect from light
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