| Identification | Back Directory | [Name]
5'-O-(4,4-Dimethoxytrityl)-2'-O-methyl-N-isobutyrylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite | [CAS]
150780-67-9 | [Synonyms]
2'-OMe-ibu-G Phosphoramidite
ibu-2'-OMe-G Phosphoramidite
2'-OMe-G(ibu) Phosphoramidite
2'-OMe-G(iBu)-3'-phosphoramidit
2'-OMe-G(iBu)-3'-phosphoramidite
5'-O-DMT-2'-O-Me-rG(N-iBu)-3'-CEDPA
2’-O-Methy-rG(N-ibu)Phosphoramidite
DMT-2'-OME-dG(Bz)-CE-Phosphoramidite
DMT-2′O-Methyl-rG(ib) Phosphoramidite
5'-O-DMT-2'-O-Me-G(ibu) phosporamidite
2'-O-methylguanosine-ce phosphoramidite for abi
N-blocked-5'-O-DMT-2'-O-Me CED guanosine phosphoramidite
5'-O-DMTr-N2-iBu-2'-O-Me-guanosine-3'-CED phosphoramidite
2'-O-Methyl-N2-Isobutyryl-5'-O-DMT-Guanosine-3'-CE-Phosphoramidite
N2-isobutyryl-5'-O-(4, 4'-Dimethoxytrityl)-2'-O-methyl-Guanosine-3'-CE-Phosphoramidite
5'-O-(4,4-Dimethoxytrityl)-2'-O-methyl-N-isobutyrylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyroyl-2'-O-methylguanosine-3'-O-[(2-cyanoethyl)(N,N-diisopropyl)]-phosphoramidite
Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-N-(2-methyl-1-oxopropyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] | [EINECS(EC#)]
2017-001-1 | [Molecular Formula]
C45H56N7O9P | [MDL Number]
MFCD00792625 | [MOL File]
150780-67-9.mol | [Molecular Weight]
869.94 |
| Chemical Properties | Back Directory | [Melting point ]
138 - 140°C | [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly, Sonicated) | [form ]
powder | [pka]
9.16±0.20(Predicted) | [color ]
white to off-white | [InChIKey]
IRRDHRZUOZNWDJ-MLLDKZSOSA-N | [SMILES]
O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C3=C(C(NC(=N3)NC(=O)C(C)C)=O)N=C2)[C@H](OC)[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,44,47,r| |
| Hazard Information | Back Directory | [Chemical Properties]
The IUPAC Name is N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-methoxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
| [Uses]
2''-OMe-ibu-G Phosphoramidite (CAS# 150780-67-9) is used in the synthesis of native-like crosslinked duplex RNA via interstrand crosslinking reaction between vinylpurine on one strand and target cytosine or uracil on the opposite strand. | [Definition]
2'-OMe-G(iBu)-3'-phosphoramidite is a chemically unstable and heat-sensitive nucleoside phosphoramidite that serves as a foundational element in oligonucleotide synthesis. | [storage]
4°C, protect from light |
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