| Identification | Back Directory | [Name]
2’-O-Methyl-rA(N-Bz)phosphoramidite | [CAS]
110782-31-5 | [Synonyms]
Ac-dA Phosphoramidite
-2-((bis(4-methoxyphenyl)
2'OMe-A CE PhosphoraMidite
Bz-2'-OMe-rA Phosphoramidite
2'-OMe-A(Bz) Phosphoramidite
2'-OMe-Bz-A Phosphoramidite
-5-(6-Benzamido-9H-purin-9-yl)
2'-OMe-Bz-rA -CE Phosphoramidite
5'-O-DMT-2'-O-Me-rA(N-Bz)-3'-CEDPA
2’-O-Methyl-rA(N-Bz)phosphoramidite
DMT-2'-OME-dA(Bz)-CE-Phosphoramidite
DMT-2′O-Methyl-rA(bz) Phosphoramidite
5'-DMT-2'-OMe-rA(N-Bz) Phosphoramidite
5'-O-DMT-2'-O-Me-A(bz) phosphoramidite
5'-O-DMT-2'-OMe-Bz-A-CE-Phosphoramidite
-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl)
2'-O-methyladenosine-ce phosphoramidite for abi
N-blocked-5'-O-DMT-2'-O-Me CED adenosine phosphoramidite
N6-Benzoyl-5'-O-DMT-2'-O-methyladenosine 3'-CE phosphoramidite
2'-O-Methyl-N6-Benzoyl-5'-O-DMT-Adenosine-3'-CE-Phosphoramidite
N6-Benzoyl-5'-O-DMT-2'-O-methyl-D-adenosine 3'-CE phosphoramidite
N6-benzoyl-5'-O-(4, 4'-Dimethoxytrityl)-2'-O-methyl-Adenosine-3'-CE-Phosphoramidite
N-[9-(5-{[BIS(4-METHOXYPHENYL)(PHENYL)METHOXY]METHYL}-4-{[(2-CYANOETHOXY)(DIISOPROPYLAMINO)PHOSPHANY
5'-DiMethoxytrityl-N-benzoyl-Adenosine,2'-O-Methyl, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoraMidite
N-Benzoyl-5'-O-(4,4-dimethoxytrityl)-2'-O-methyladenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl adenosine-3'-O-[(2-cyanoethyl)(N,N-diisopropyl)]-phosphoramidite
Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
(2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite | [EINECS(EC#)]
200-100-5 | [Molecular Formula]
C48H54N7O8P | [MDL Number]
MFCD00792622 | [MOL File]
110782-31-5.mol | [Molecular Weight]
887.96 |
| Chemical Properties | Back Directory | [Melting point ]
93-95°C | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
Acetonitrile (Sparingly), DMSO (Slightly), Methanol (Slightly) | [form ]
powder | [pka]
7.87±0.43(Predicted) | [color ]
white to off-white | [InChIKey]
AZCGOTUYEPXHMJ-DCATYJMPNA-N |
| Hazard Information | Back Directory | [Chemical Properties]
White or off-white power | [Uses]
(2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite is a nucleotide used in the synthesis of native-like crosslinked duplex RNA. | [General Description]
Proligo′s 2′O-Methyl RNA monomers are compatible with fast deprotectionschemes that are based on the application of aliphatic amines, such asmethylamine. The adenosine and guanosine monomers are protected bythe standard benzoyl (bz) and isobutyryl (ib) groups.2′O-Methyl RNA is a nucleic acid analog that is characterized by theexceptional hybridization properties that it imparts with complimentary DNA or RNA, as well as increased stability against enzymatic degradationcompared to natural nucleic acids.The unique combination of properties of 2′O-Methyl RNA had foundwidespread use in the fields of:
Diagnostic probes
Aptamer and ribozyme development
Mixed 2′O-Methyl-RNA/DNA antisense molecules
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