| Identification | More | [Name]
2-Amino-3-picoline | [CAS]
1603-40-3 | [Synonyms]
2-AMINO-3-METHYLPYRIDINE
2-AMINO-3-PICOLINE
2-Amino-β-picoline
3-METHYL-2-PYRIDYLAMINE
3-METHYLPYRIDIN-2-AMINE
3-METHYLPYRIDIN-2-YLAMINE
Amino-3-methyl pyridine
AURORA KA-876
TIMTEC-BB SBB004356
2-amino-3-methyl-pyridin
2-Amino-beta-picoline
2-Pyridinamine,3-methyl-
3-Methyl-2-aminopyridine
3-methyl-2-pyridinamin
3-Methyl-2-pyridinamine
3-Picoline, 2-amino-
Pyridine, 2-amino-3-methyl-
2-Amino-3-methylpyridine,97%
2-Amino-3-picoline
2-Amino-3-methylpyridine
2-Pyridinamine,3-methyl-(9CI) | [EINECS(EC#)]
216-501-4 | [Molecular Formula]
C6H8N2 | [MDL Number]
MFCD00006320 | [Molecular Weight]
108.14 | [MOL File]
1603-40-3.mol |
| Chemical Properties | Back Directory | [Appearance]
CLEAR YELLOW LIQUID AFTER MELTING | [Melting point ]
29-31 °C (lit.) | [Boiling point ]
221-222 °C (lit.) | [density ]
1.073 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.5823(lit.)
| [Fp ]
233 °F
| [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
1000g/l | [form ]
Liquid After Melting | [pka]
pK1: 7.24(+1) (25°C) | [color ]
Clear yellow | [Water Solubility ]
SOLUBLE | [Sensitive ]
Hygroscopic | [Detection Methods]
HPLC | [BRN ]
107892 | [InChIKey]
RGDQRXPEZUNWHX-UHFFFAOYSA-N | [CAS DataBase Reference]
1603-40-3(CAS DataBase Reference) | [NIST Chemistry Reference]
2-Pyridinamine, 3-methyl-(1603-40-3) | [EPA Substance Registry System]
1603-40-3(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
T | [Risk Statements ]
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed .
R33:Danger of cumulative effects.
R36/37/38:Irritating to eyes, respiratory system and skin .
R25:Toxic if swallowed. | [Safety Statements ]
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S37/39:Wear suitable gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [RIDADR ]
UN 2811 6.1/PG 3
| [WGK Germany ]
3
| [RTECS ]
US1850000
| [TSCA ]
Yes | [HazardClass ]
6.1 | [PackingGroup ]
II | [HS Code ]
29333999 |
| Hazard Information | Back Directory | [Chemical Properties]
2-Amino-3-picoline is CLEAR YELLOW LIQUID AFTER MELTING
| [Uses]
2-Amino-3-picoline is used in the synthesis of ketones from aldehydes.
| [Synthesis Reference(s)]
Journal of the American Chemical Society, 95, p. 4453, 1973 DOI: 10.1021/ja00794a070 | [Hazard]
Toxic by ingestion. | [Purification Methods]
Recrystallise the picoline three times from *benzene, most of the residual *benzene being removed from the crystals by standing over paraffin wax chips in an evacuated desiccator. The amine is also transferred to a separating funnel under N2, and left in contact with NaOH pellets for 3hours with occasional shaking. It is then placed in a vacuum distilling flask where it is refluxed gently in a stream of dry N2 before fractionally distilling it. [Mod et al. J Phys Chem 60 1651 1956, Beilstein 22/9 V 212]. |
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