| Identification | More | [Name]
4-Deoxypyridoxine hydrochloride | [CAS]
148-51-6 | [Synonyms]
4-DEOXYPYRIDOXINE HCL
4-DEOXYPYRIDOXINE HYDROCHLORIDE
5-HYDROXY-4,6-DIMETHYL-3-PYRIDINEMETHANOL HYDROCHLORIDE
DEOXYPYRIDOXINE, 4-HCL
4,6-dimethyl-5-hydroxy-3-pyridinemethanohydrochloride
4-deoxypyridoxolhydrochloride
5-hydroxy-4,6-dimethyl-3-pyridinemethanohydrochloride
desoxypyridoximehydrochloride
nsc3063
3-hydroxy-5-hydroxymethyl-2,4-dimethylpyridinium chloride
4-deoxypyridoxine hydrochloride*crystalline
5-(Hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloride
Deoxypyridoxine hydrochloride | [EINECS(EC#)]
205-714-8 | [Molecular Formula]
C8H12ClNO2 | [MDL Number]
MFCD00051296 | [Molecular Weight]
189.64 | [MOL File]
148-51-6.mol |
| Hazard Information | Back Directory | [Description]
4-deoxy Pyridoxine (DOP) is a vitamin B6 antimetabolite with diverse biological activities.1,2,3,4,5 It inhibits transport of pyridoxine (Item No. 20706), pyridoxal, and pyridoxamine in and reduces growth of S. carlsbergensis cells.1 DOP inhibits sphingosine-1-phosphate (S1P) lyase and reduces cyclic stretch-induced apoptosis in alveolar epithelial MLE-12 cells.2 DOP (5 mg, i.p.) reduces lysyl oxidase activity by 26% and reduces collagen and elastin crosslinking, resulting in limb abnormalities in chick embryos.3 It decreases latency to first seizure in mice (ED50 = 1 mmol/kg) and increases the occurrence and duration of myoclonic responses in baboons with photosensitive epilepsy.4 DOP reduces TNF-α and IL-6 production in mice infected with T. spiralis.5 | [Chemical Properties]
Solid | [Uses]
4-Deoxypyridoxine is the deoxy analogue of Pyridoxine (P991735). 4-Deoxypyridoxine is a vitamin B6 antimetabolite; 4-Deoxypyridoxine can induce a deficient status that alters the function and ultrastructure of EC similar to vascular disease. |
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