| Identification | Back Directory | [Name]
N,N'-DINITROSOPIPERAZINE | [CAS]
140-79-4 | [Synonyms]
Dnpz
nsc339
NSC 339
usafdo-36
USAF do-36
Dinitrosopiperazin
Dinitrosopiperazine
TIMTEC-BB SBB008187
Piperazine Impurity 4
Piperazine Impurity 24
N,N-Dinitroso-Piperazin
1,4-DINITROSOPIPERAZINE
1,4-dinitrosopiperidine
1,4-dinitroso-piperazin
N,N'-DINITROSOPIPERAZINE
N,N'-DINITROSOPIPERAZINE
Piperazine, 1,4-dinitroso-
N- Nitrosopiperazine DIMER
N,N'-Dinitrosopiperazine (DMP)
140-79-4---N,N'-DINITROSOPIPERAZINE
1,4-Dinitrosopiperazine in acetonitrile
Dinitrosopiperazine: (Piperazine, 1,4-dinitroso-) | [EINECS(EC#)]
205-434-6 | [Molecular Formula]
C4H8N4O2 | [MDL Number]
MFCD00014615 | [MOL File]
140-79-4.mol | [Molecular Weight]
144.13 |
| Chemical Properties | Back Directory | [Melting point ]
208-210°C | [Boiling point ]
262.72°C (rough estimate) | [density ]
1.4165 (rough estimate) | [refractive index ]
1.8500 (estimate) | [storage temp. ]
-20°C Freezer, Under Inert Atmosphere | [solubility ]
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
-4.82±0.70(Predicted) | [color ]
White to Pale Yellow | [Water Solubility ]
5.765g/L(24 ºC) | [Stability:]
Hygroscopic | [CAS DataBase Reference]
140-79-4 | [EPA Substance Registry System]
Piperazine, 1,4-dinitroso- (140-79-4) |
| Hazard Information | Back Directory | [Chemical Properties]
Pale Yellow Solid | [Uses]
N,N'-Dinitrosopiperazine (DNP) induces nasopharyngeal carcinoma (NPC) and shows organ specificity to the nasopharyneal epithelium. | [in vivo]
N,N'-Dinitrosopiperazine (injected into the tail veins; 40 mg/kg; 30 days) inhibits cell motility and invasion, and facilitates NPC metastasis in vivo. From a IHC result, Phospho-LYRIC expression is higher in the metastatic tumors of DNP-treated mice than in those of the untreated control mice[1]. | Animal Model: | BABL/c nude mice injected with labeled 6-10B cell suspensions (1?×?104?cells) with or without DNP(40 mg/kg)[1] | | Dosage: | 40 mg/kg | | Administration: | Injected into the tail veins; 30 days | | Result: | Induced LYRIC phosphorylation at serine 568 associated with NPC metastasis in vivo. |
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| Company Name: |
Riddhesh Pharmachem
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| Tel: |
+91-9106014993 +91-9106014993 |
| Website: |
www.riddheshpharmachem.com |
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