| Identification | More | [Name]
Glycolonitrile | [CAS]
107-16-4 | [Synonyms]
2-HYDROXYACETONITRILE
2-Hydroxymethylnitrile
cyanomethanol
FORMALDEHYDE CYANHYDRIN
FORMALDEHYDE CYANOHYDRIN
GLYCOLIC ACID NITRILE
GLYCOLONITRILE
HYDROXYACETONITRILE
2-Hydroxyethanenitrile
alpha-hydroxyacetonitrile
alpha-hydroxymethylcyanide
Cyanomethanol,glycolonitrile
Glycolic nitrile
glycolicacidnitrilesolution
glycolicnitrile
Glyconitrile
Glykolonitril
HOCH2CN
hydroxy-acetonitril
Hydroxyactonitrile | [EINECS(EC#)]
203-469-1 | [Molecular Formula]
C2H3NO | [MDL Number]
MFCD00042731 | [Molecular Weight]
57.05 | [MOL File]
107-16-4.mol |
| Chemical Properties | Back Directory | [Appearance]
Formaldehyde cyanohydrin is a colorless,
odorless, oily liquid. Sweet taste (very highly toxic; do not
test). | [Melting point ]
-72°C | [Boiling point ]
183°C | [density ]
1.076 g/mL at 20 °C
| [refractive index ]
n20/D 1.389
| [Fp ]
133 °F
| [pka]
11.31±0.10(Predicted) | [Stability:]
Stable, but may react violently with alkalies. Incompatible with strong oxidizing agents. | [Water Solubility ]
>=10 g/100 mL at 20 ºC | [Dielectric constant]
27.0（20℃） | [Uses]
Solvent and organic intermediate. | [CAS DataBase Reference]
107-16-4(CAS DataBase Reference) | [NIST Chemistry Reference]
Acetonitrile, hydroxy-(107-16-4) | [EPA Substance Registry System]
107-16-4(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
T+ | [Risk Statements ]
R26/27/28:Very Toxic by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 3276 6.1/PG 1
| [WGK Germany ]
-
| [RTECS ]
AM0350000
| [HazardClass ]
6.1(a) | [PackingGroup ]
I | [Hazardous Substances Data]
107-16-4(Hazardous Substances Data) | [Toxicity]
mouse,LCLo,inhalation,27ppm/8H (27ppm),BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE,"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 290, 1969. |
| Hazard Information | Back Directory | [General Description]
Odorless colorless oil with a sweetish taste. Used in the manufacture of intermediates in pharmaceutical production, as a component of synthetic resins, as a chemical intermediate for organic compounds, and as a solvent. | [Reactivity Profile]
FORMALDEHYDE CYANOHYDRIN(107-16-4) may undergo spontaneous and violent decomposition. Traces of alkali (base) promote violent polymerization [Lewis]. | [Air & Water Reactions]
Water soluble. | [Hazard]
Toxic by ingestion, inhalation, and skin
absorption. | [Health Hazard]
Extremely toxic, exposure by any route should be avoided; may have fatal consequences; death from asphyxiation may occur similar to that resulting from hydrogen cyanide. | [Potential Exposure]
Formaldehyde cyanohydrin is used in
the manufacture of intermediates in pharmaceutical produc tion and as a component of synthetic resins as a chemical
intermediate for organic compounds, and as a solvent. | [Fire Hazard]
Moderate explosion hazard when exposed to heat or by spontaneous chemical reaction in the presence of alkalies if uninhibited. When heated to decomposition, FORMALDEHYDE CYANOHYDRIN emits highly toxic fumes of cyanide and nitrogen oxides. Unstable, may explode on standing. Hazardous polymerization may occur. avoid the presence of alkalis, and exposure to heat. | [First aid]
If this chemical gets into the eyes, remove any
contact lenses at once and irrigate immediately for at least
15 minutes, occasionally lifting upper and lower lids. Seek
medical attention immediately. If this chemical contacts the
skin, remove contaminated clothing and wash immediately
with soap and water. Speed in removing material from skin
is of extreme importance. Seek medical attention immedi ately. If this chemical has been inhaled, remove from expo sure, begin rescue breathing (using universal precautions,
including resuscitation mask) if breathing has stopped and
CPR if heart action has stopped. Transfer promptly to a
medical facility. When this chemical has been swallowed,
get medical attention. Give large quantities of water and
induce vomiting. Do not make an unconscious person vomit.
Keep victim quiet and maintain normal body temperature.
Effects may be delayed; keep victim under observation. Use
amyl nitrate capsules if symptoms develop. All area employ ees should be trained regularly in emergency measures for
cyanide poisoning and in CPR. A cyanide antidote kit should
be kept in the immediate work area and must be rapidly
available. Kit ingredients should be replaced every 1 2
years to ensure freshness. Persons trained in the use of this
kit; oxygen use, and CPR must be quickly available. | [Shipping]
UN3276 Nitriles, liquid, toxic, n.o.s., Hazard
Class: 6.1; Labels: 6.1-Poisonous materials, Technical
Name Required, Potential Inhalation Hazard (Special
Provision 5). UN2810 Toxic liquids, organic, n.o.s., Hazard
Class: 6.1; Labels: 6.1-Poisonous materials, Technical
Name Required. | [Incompatibilities]
Incompatible with oxidizers (chlorates,
nitrates, peroxides, permanganates, perchlorates, chlorine,
bromine, fluorine, etc.); contact may cause fires or explo sions. Keep away from alkaline materials, strong bases,
strong acids, oxoacids, epoxides, and exposure to heat.
Unless stabilized with a weak acid solution, traces of alka lis may cause violent polymerization. | [Description]
Formaldehyde cyanohydrin is a colorless,odorless oily liquid with a sweetish taste. Molecularweight=57.06; Boiling point=186℃ (slight decomposition); Freezing/Melting point #272℃; Flash point≥93℃. Hazard Identification (based on NFPA-704 MRating System): Health 4, Flammability 2, Reactivity 2.Soluble in water. | [Chemical Properties]
Formaldehyde cyanohydrin is a colorless,
odorless, oily liquid. Sweet taste (very highly toxic; do not
test). | [Chemical Properties]
light yellow liquid (typically available as a concentrated | [Definition]
ChEBI: Glycolonitrile is an cyanohydrin that is acetonitrile in which one of the hydrogens has been replaced by a hydroxy group. | [Production Methods]
Glycolonitrile is the result of reaction between formaldehyde
and aqueous sodium cyanide in the presence of mineral acid. | [storage]
Color Code—Blue: Health Hazard/Poison: Store ina secure poison location. Prior to working with this chemicalyou should be trained on its proper handling and storage.Store in a refrigerator under an inert atmosphere and awayfrom all alkaline materials. Where possible, automaticallypump liquid from storage containers to process containers. |
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