| Identification | More | [Name]
Eprazinone | [CAS]
10402-90-1 | [Synonyms]
1-(2-phenyl-2-ethoxy)ethyl-4-(2-benzoyl)propylpiperazine
EPRAZINONE
1-Propanone, 3-[4-(2-ethoxy-2-phenylethyl)-1-piperazinyl]-2-methyl-1-phenyl-
1-(2-phenyl-2-ethoxyethyl)-4-(2-benzyloxypropyl)piperazine
2-(4-(beta-ethoxyphenethyl)-1-piperazinyl)methyl-propiophenon
3-(4-(2-ethoxy-2-phenylethyl)-1-piperazinyl)-2-methyl-1-phenyl-1-propano ne
3-(4-(beta-ethoxyphenethyl)-1-piperazinyl)-2-methylpropiophenone
Eprazinone (base and/or unspecified salts)
β-[4-(β-Ethoxyphenethyl)-1-piperazinyl]-α-methylpropiophenone | [EINECS(EC#)]
233-873-3 | [Molecular Formula]
C24H32N2O2 | [MDL Number]
MFCD00866843 | [Molecular Weight]
380.52 | [MOL File]
10402-90-1.mol |
| Hazard Information | Back Directory | [Originator]
Mucitux,Riom,France,1969 | [Definition]
ChEBI: A member of the class of piperazines in which the two amino hydrogens of piperazine are replaced by 2-benzoylpropyl and 2-ethoxy-2-phenylethyl groups. | [Manufacturing Process]
61.4 g of 0.2M of 1-(2-phenyl-2-ethoxy)piperazine dihydrochloride, 33.5 g
(0.25M) propiophenone, 75 g (0.25M) trioxymethylene, 120 ml of ethanol and
0.4 ml of concentrated HCl are heated under reflux for 4 to 5 hours. The
product is allowed to crystallize, then filtered and washed with alcohol. It is
dried and recrystallized from methanol containing 10% H2O.
There is thus obtained 60 g of a white crystalline powder soluble in water.
Yield: 66%. Melting point: 160°C. | [Therapeutic Function]
Antitussive |
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