| Identification | More | [Name]
N-Ethylmorpholine | [CAS]
100-74-3 | [Synonyms]
4-ETHYLMORPHOLINE
LUPRAGEN(R) N 104
N-ETHYLMORPHOLINE
4-ethyl-morpholin
Dabco NCM, NEM, NMM
Ethylmorpholine
HEM
n-ethvlmorpholine
N-Ethyldiethylenimideoxide
N-Ethylmorfolin
N-Ethyltetrahydro-1,4-oxazine
Texacat NEM
Toyocat-NEM
4-ETHYLMORPHOLINE, FOR PROTEIN SEQUENCE ANALYSIS
N-ETHYLMORPHOLINE 99%
N-Ethyl-MorpholineForSynthesis
4-Ethylmorhpoline
Morpholine, 4-ethyl- | [EINECS(EC#)]
202-885-0 | [Molecular Formula]
C6H13NO | [MDL Number]
MFCD00006177 | [Molecular Weight]
115.17 | [MOL File]
100-74-3.mol |
| Chemical Properties | Back Directory | [Appearance]
4-Ethylmorpholine is a colorless liquid with
an ammonia-like odor. | [Melting point ]
-63 °C (lit.) | [Boiling point ]
139 °C (lit.) | [density ]
0.91 g/mL at 20 °C(lit.)
| [vapor pressure ]
8.1 hPa (20 °C) | [refractive index ]
n20/D 1.441(lit.)
| [Fp ]
82 °F
| [storage temp. ]
Flammables area | [solubility ]
miscible | [form ]
Powder | [pka]
7.67(at 25℃) | [color ]
Cream to beige to brown-grey | [PH]
11.8 (100g/l, H2O, 20℃) | [Stability:]
Stable. Flammable. Incompatible with strong oxidizing agents. Slightly air sensitive. | [explosive limit]
1.9%(V) | [Water Solubility ]
miscible | [FreezingPoint ]
-63℃ | [Sensitive ]
Air Sensitive | [BRN ]
102969 | [Exposure limits]
NIOSH REL: TWA 5 ppm (23 mg/m3), IDLH 100 ppm; OSHA PEL: TWA 20
ppm (94 mg/m3); ACGIH TLV: TWA 5 ppm (adopted). | [Uses]
Intermediate for dyestuffs, pharmaceuticals;
rubber accelerators and emulsifying agents; solvent for dyes, resins, oils; catalyst in making
polyurethane foams. | [CAS DataBase Reference]
100-74-3(CAS DataBase Reference) | [NIST Chemistry Reference]
Morpholine, 4-ethyl-(100-74-3) | [EPA Substance Registry System]
100-74-3(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
C | [Risk Statements ]
R10:Flammable.
R21/22:Harmful in contact with skin and if swallowed .
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S16:Keep away from sources of ignition-No smoking . | [RIDADR ]
UN 2920 8/PG 2
| [WGK Germany ]
1
| [RTECS ]
QE4025000
| [F ]
8-23 | [Autoignition Temperature]
160 °C | [TSCA ]
Yes | [HazardClass ]
8 | [PackingGroup ]
II | [HS Code ]
29349990 | [Safety Profile]
oison by intravenous
route. Moderately toxic by ingestion. Mildly
toxic by inhalation. A skin and severe eye
irritant. A very dangerous fire hazard when
exposed to heat or flame; can react
vigorously with oxidzing materials. To fight
fire, use alcohol foam, foam, CO2, dry
chemical. When heated to decomposition it
emits toxic fumes of NOx. | [Hazardous Substances Data]
100-74-3(Hazardous Substances Data) | [Toxicity]
LD50 orally in Rabbit: 1640 mg/kg LD50 dermal Rabbit 900 mg/kg | [IDLA]
100 ppm |
| Hazard Information | Back Directory | [General Description]
A colorless liquid with a strong ammonia-like odor. Severely irritates skin, eyes, and mucous membranes. Moderately soluble in water and less dense than water. Flash point 83°F . | [Reactivity Profile]
N-ETHYL MORPHOLINE(100-74-3) can react vigorously with oxidizing materials. N-ETHYL MORPHOLINE(100-74-3) dissolves LiAlH4. | [Air & Water Reactions]
Highly flammable. Moderately soluble in water . | [Hazard]
Irritant to skin and eyes, absorbed by
skin. Flammable, moderate fire risk. Toxic by skin
absorption. | [Health Hazard]
Exposure can cause irritation of eyes, nose and throat. Contact with eyes may result in foggy vision and seeing halos around lights. | [Potential Exposure]
Primary irritant (without allergic reaction). This material is used as a catalyst in polyurethane
foam production. It is a solvent for dyes and resins. It is
used as an intermediate in surfactant, dye, pharmaceutical,
and rubber chemical manufacture | [First aid]
If this chemical gets into the eyes, remove any
contact lenses at once and irrigate immediately for at least
15 minutes, occasionally lifting upper and lower lids. Seek
medical attention immediately. If this chemical contacts the
skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately.
If this chemical has been inhaled, remove from exposure,
begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if
heart action has stopped. Transfer promptly to a medical
facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce
vomiting. Do not make an unconscious person vomit.
| [Shipping]
UN2920 Corrosive liquids, flammable, n.o.s.,
Hazard class: 8; Labels: 8-Corrosive material, 3-Flammable
liquid. UN1993 Flammable liquids, n.o.s., Hazard Class: 3;
Labels: 3-Flammable liquid, Technical Name Required | [Incompatibilities]
May form explosive mixture with air.
Incompatible with oxidizers (chlorates, nitrates, peroxides,
permanganates, perchlorates, chlorine, bromine, fluorine,etc.); contact may cause fires or explosions. Keep away
from alkaline materials, strong bases, strong acids, oxoacids, and epoxides. Corrodes some metals. Unless inhibited,
violent polymerization can occur from heat, sunlight, and
contact with strong oxidizers permanganates, perchlorates, chlorine, bromine, fluorine,
etc.); contact may cause fires or explosions. Keep
away from alkaline materials, strong bases, strong acids,
oxoacids, and epoxides. Attacks some plastics, rubber and
coatings | [Chemical Properties]
4-Ethylmorpholine is a colorless liquid with
an ammonia-like odor. | [Chemical Properties]
colourless liquid | [Waste Disposal]
Controlled incineration (oxides of nitrogen are removed from the effluent gas by scrubbers and/or thermal devices).
| [Physical properties]
Colorless, flammable liquid with an ammonia-like odor. Experimentally determined detection and
recognition odor threshold concentrations were 400 μg/m3 (85 ppbv) and 1.2 mg/m3 (250 ppbv),
respectively (Hellman and Small, 1974). | [Preparation]
N-Ethylmorpholine is synthesized by the reaction of morpholine with bromoethane. | [Synthesis Reference(s)]
The Journal of Organic Chemistry, 56, p. 678, 1991 DOI: 10.1021/jo00002a035
Tetrahedron Letters, 37, p. 6749, 1996 DOI: 10.1016/S0040-4039(96)01458-X | [Flammability and Explosibility]
Flammable | [Environmental Fate]
Chemical/Physical. Releases toxic nitrogen oxides when heated to decomposition (Sax and
Lewis, 1987).
At an influent concentration of 1,000 mg/L, treatment with GAC resulted in an effluent
concentration of 467 mg/L. The adsorbability of the carbon used was 107 mg/g carbon (Guisti et
al., 1974). |
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