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636-60-2

Pyrotartaric acid synthesis

12synthesis methods
-

Yield:636-60-2 84 %Spectr.

Reaction Conditions:

with hydrogen in water at 225; under 6000.6 Torr; for 0.666667 h;Pressure;

Steps:

27 EXAMPLES 26-28

General procedure: 42 mg of citric acid monohydrate was dissolved in 2 mL of water, 0.5 mol% of Pd (catalyst in powder form) was added and the reactor was flushed 6 times with N2. Then the reactor was loaded with H2 and heated to 225°C for a period of 40 min. The conversion of citric acid was >99% in all cases. Example 27 shows that a proper combination of H2 pressure, time and temperature also allows to reach high yields with a minimal amount of the commercial Pd/C catalyst.

References:

WO2018/65475,2018,A1 Location in patent:Page/Page column 15