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ChemicalBook CAS DataBase List PF-06282999
1435467-37-0

PF-06282999 synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1.1: magnesium ethylate / tetrahydrofuran / 4 h / 45 °C
1.2: 23 h / 20 - 45 °C
2.1: sodium methylate / methanol / 1 h / 65 °C
2.2: 16 h / 50 °C / Reflux
3.1: acetic acid butyl ester / 15 h / Reflux

References:

Carpino, Philip A.;Conn, Edward L.;Dow, Robert L.;Dowling, Matthew S.;Hepworth, David;Kung, Daniel Wei-Shung;Orr, Suvi;Rocke, Benjamin N.;Ruggeri, Roger B.;Sammons, Matthew F.;Warmus, Joseph S.;Zhang, Yan US2013/123230, 2013, A1

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