4′-Methylbiphenyl-2-carboxylic acid methyl ester synthesis
- Product Name:4′-Methylbiphenyl-2-carboxylic acid methyl ester
- CAS Number:114772-34-8
- Molecular formula:C15H14O2
- Molecular Weight:226.27
67-56-1
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$7.29/5ml-f
7148-03-0
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$10.00/1g
114772-34-8
299 suppliers
$12.00/1g
Yield:114772-34-8 98.05%
Reaction Conditions:
with dmap;dicyclohexyl-carbodiimide at 25; for 3 h;Large scale;Temperature;
Steps:
1.2 preparation of 4'-methylbiphenyl-2-carboxylic acid methyl ester
To the kettle was added 5.30 kg4 & ' -methyl-2-carboxylic acid biphenyl,Anhydrous methanol 10. 60 kg,5. 83 kg DCC,0. 09 kg DMAP,25 ° C reaction for 3 hours,After filtration, the filtrate into another reactor, adding 50. 00kg of water, stirring crystallization, and then centrifuged, washed to neutral, 40 ° C vacuum drying 24 hours to get 5. 54kg4 '- methyl -2-- Formate biphenyl,Melting point 55 ~ 57 ° C, yield 98. 05%, purity 99. 06%.
References:
weite hunan pharmaceutical co ltd;He, liang;Luo, hui;Mo, wei CN105399627, 2016, A Location in patent:Paragraph 0056; 0057
610-96-8
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380481-66-3
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114772-34-8
299 suppliers
$12.00/1g
7148-03-0
225 suppliers
$10.00/1g
18107-18-1
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$33.00/5g
114772-34-8
299 suppliers
$12.00/1g
![methyl 2-[(methylsulfonyl)oxy]benzoate](/CAS/20180711/GIF/95667-98-4.gif)
610-94-6
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5720-05-8
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$5.00/1g
114772-34-8
299 suppliers
$12.00/1g