Methyl 3-bromobenzoate synthesis
- Product Name:Methyl 3-bromobenzoate
- CAS Number:618-89-3
- Molecular formula:C8H7BrO2
- Molecular Weight:215.04
585-76-2
345 suppliers
$6.00/5g
618-89-3
261 suppliers
$28.00/5g
Yield:618-89-3 85%
Reaction Conditions:
with sulfuric acid in methanol;dichloromethane;ethyl acetate
Steps:
2.A Methyl 3-(2-α-L-fucopyranosyloxy)phenyl)benzoate
Part A: 3-Bromobenzoic acid (1.1 g, 5.47 mmol) was dissolved in methanol (20 ml) in a 50 ml flask. Concentrated sulfuric acid (2 drops) was added and the mixture was refluxed under nitrogen for ten hours then concentrated under reduced pressure. The residue was mixed with dichloromethane (20 ml) and saturated sodium bicarbonate solution (10 ml). The organic material was separated, dried (MgSO4) and concentrated under reduced pressure. The residue was flushed through silica gel with hexane/ethyl acetate (3:1), and concentrated which provided methyl 3-bromobenzoate (1.0 g, 85%).
References:
Texas Biotechnology Corporation US5622937, 1997, A
93-58-3
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$13.50/100 mL
618-89-3
261 suppliers
$28.00/5g
75-91-2
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$26.00/100g
591-17-3
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$10.00/10g
618-89-3
261 suppliers
$28.00/5g
67-56-1
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$7.29/5ml-f
15852-73-0
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$11.00/25g
618-89-3
261 suppliers
$28.00/5g