METHYL 1-METHOXY-2-NAPHTHOATE synthesis
- Product Name:METHYL 1-METHOXY-2-NAPHTHOATE
- CAS Number:6039-59-4
- Molecular formula:C13H12O3
- Molecular Weight:216.23
Yield:6039-59-4 100%
Reaction Conditions:
with potassium carbonate in acetone;Reflux;
Steps:
10 Synthesis of intermediate 30
50.0 g (0.265 mol) of 1-hydroxy-2-naphthoic acid, 110.2 g (0.797 mol) of potassium carbonate (K2CO3) and 1050 mL of acetone were placed in a 2 L 1-necked flask, 151 g (1.06 mol) was slowly added dropwise and then refluxed. After completion of the reaction, the inorganic matter was removed by filtration, and the solvent was removed by concentration under reduced pressure. The concentrate was extracted twice with EA, washed with saturated brine, dried over anhydrous MgSO 4 and concentrated under reduced pressure to obtain 57.45 g (yield: 100%) of a red oil compound (Intermediate (30)).
References:
KR2019/25788,2019,A Location in patent:Paragraph 0182-0184