天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List Lenalidomide
191732-72-6

Lenalidomide synthesis

11synthesis methods
-

Yield:191732-72-6 98.2%

Reaction Conditions:

with palladium-carbon;hydrogen in ethanol at 40; under 3000.3 Torr;Pressure;Temperature;

Steps:

1.2 example 1

2) 0.4 g of 3-(4-nitro-1-oxo-2,3-dihydro-1H-isoindol-2-yl)piperidine-2,6-dioneand 0.4 g of 5% palladium carbon were added to a solution of 15 ml of ethanol Kettle,Into the hydrogen (hydrogen pressure of 0.4MPa)In 40, ° C reduction reaction, the reaction was completed, filtered, the filtrate was concentrated under reduced pressure,Recrystallization of petroleum ether gave lenalidomide 21.6 g, yield 98.2%, HPLC purity 99.20%.

References:

CN107337666,2017,A Location in patent:Paragraph 0025; 0030; 0033-0034; 0037-0038; 0041-0042; 0045

Lenalidomide Related Search: